User profiles for Robert Lodge
Robert LodgeResearch Associate in Human Retrovirology at IRCM Verified email at ircm.qc.ca Cited by 4313 |
Rapid cycling of lipid raft markers between the cell surface and Golgi complex
The endocytic itineraries of lipid raft markers, such as glycosyl phosphatidylinositol (GPI)-anchored
proteins and glycosphingolipids, are incompletely understood. Here we show that …
proteins and glycosphingolipids, are incompletely understood. Here we show that …
Cation trapping by cellular acidic compartments: beyond the concept of lysosomotropic drugs
“Lysosomotropic” cationic drugs are known to concentrate in acidic cell compartments due to
low retro-diffusion of the protonated molecule (ion trapping); they draw water by an osmotic …
low retro-diffusion of the protonated molecule (ion trapping); they draw water by an osmotic …
Modulation of phagolysosome biogenesis by the lipophosphoglycan of Leishmania
R Lodge, A Descoteaux - Clinical Immunology, 2005 - Elsevier
Promastigotes of the protozoan parasite Leishmania are inoculated into the mammalian host
by an infected sandfly and are phagocytosed by macrophages. There, they differentiate into …
by an infected sandfly and are phagocytosed by macrophages. There, they differentiate into …
[HTML][HTML] A tubular EHD1‐containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane
The Eps15 homology (EH) domain‐containing protein, EHD1, has recently been ascribed a
role in the recycling of receptors internalized by clathrin‐mediated endocytosis. A subset of …
role in the recycling of receptors internalized by clathrin‐mediated endocytosis. A subset of …
Leishmania donovani lipophosphoglycan blocks NADPH oxidase assembly at the phagosome membrane
R Lodge, TO Diallo, A Descoteaux - Cellular microbiology, 2006 - Wiley Online Library
Phagocytosis of Leishmania donovani promastigotes is characterized by an inhibition of
phagolysosome biogenesis mediated by the surface glycolipid lipophosphoglycan (LPG). …
phagolysosome biogenesis mediated by the surface glycolipid lipophosphoglycan (LPG). …
[HTML][HTML] The membrane‐proximal intracytoplasmic tyrosine residue of HIV‐1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells
Budding of retroviruses from polarized epithelial Madin–Darby canine kidney cells (MDCK)
takes place specifically at the basolateral membrane surface. This sorting event is suspected …
takes place specifically at the basolateral membrane surface. This sorting event is suspected …
Rab18 and Rab43 have key roles in ER-Golgi trafficking
Rabs and Arfs/Arls are Ras-related small GTPases of particular relevance to membrane
trafficking. It is thought that these proteins regulate specific pathways through interactions with …
trafficking. It is thought that these proteins regulate specific pathways through interactions with …
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor
…, M Bor, M Szaszák, R Lodge… - The Journal of cell …, 2002 - rupress.org
Agonist-induced endocytosis and processing of the G protein–coupled AT 1 angiotensin II (Ang
II) receptor (AT 1 R) was studied in HEK 293 cells expressing green fluorescent protein (…
II) receptor (AT 1 R) was studied in HEK 293 cells expressing green fluorescent protein (…
[HTML][HTML] Divalent interaction of the GGAs with the Rabaptin‐5–Rabex‐5 complex
Cargo transfer from trans‐Golgi network (TGN)‐derived transport carriers to endosomes
involves a still undefined set of tethering/fusion events. Here we analyze a molecular interaction …
involves a still undefined set of tethering/fusion events. Here we analyze a molecular interaction …
Mechanisms of interaction between protozoan parasites and HIV
… Andreani, Guadalupe a,1 ; Lodge, Robert a,b,1 ; Richard, Dave a,b ; Tremblay, Michel J. a,b …
Garg R, Lodge R, Descoteaux A, Tremblay MJ. Leishmania infantum promastigotes reduce …
Garg R, Lodge R, Descoteaux A, Tremblay MJ. Leishmania infantum promastigotes reduce …