We report the draft genome of the black cottonwood tree, Populus trichocarpa. Integration of
shotgun sequence assembly with genetic mapping enabled chromosome-scale …

A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …

The new software package OpenMx 2.0 for structural equation and other statistical modeling
is introduced and its features are described. OpenMx is evolving in a modular direction and …

Histone deacetylases (HDACs) represent an expanding family of protein modifying-enzymes
that play important roles in cell proliferation, chromosome remodeling, and gene …

Histone acetylation alters chromatin state by modifying lysines on histone and plays an
important role in modulating gene transcription. A dynamic balance of histone acetylation/…

We have recently reported the identification of four novel members of the interleukin-1 (IL-1)
family which we designated as IL-1 homologue 1–4 (IL-1H1–4). These proteins exhibit …

This essay describes the various problems China faces on account of its exam-centric
education system and pedagogy. Along with interviews and focus groups, this study draws on …

Increased Rho kinase (ROCK) activity contributes to smooth muscle contraction and regulates
blood pressure homeostasis. We hypothesized that potent and selective ROCK inhibitors …

Although therapeutic interventions of signal-transduction cascades with targeted kinase
inhibitors are a well-established strategy, drug-discovery efforts to identify targeted phosphatase …

Conifers are resistant to attack from a large number of potential herbivores or pathogens.
Previous molecular and biochemical characterization of selected conifer defence systems …