The Genome of Black Cottonwood, Populus trichocarpa (Torr. & Gray)
…, J Kangasjarvi, J Karlsson, C Kelleher, R Kirkpatrick… - science, 2006 - science.org
We report the draft genome of the black cottonwood tree, Populus trichocarpa. Integration of
shotgun sequence assembly with genetic mapping enabled chromosome-scale …
shotgun sequence assembly with genetic mapping enabled chromosome-scale …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
…, MR Järvelin, M Kähönen, J Kaprio, RM Kirkpatrick… - science, 2013 - science.org
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
OpenMx 2.0: Extended structural equation and statistical modeling
The new software package OpenMx 2.0 for structural equation and other statistical modeling
is introduced and its features are described. OpenMx is evolving in a modular direction and …
is introduced and its features are described. OpenMx is evolving in a modular direction and …
Identification of novel isoform-selective inhibitors within class I histone deacetylases
E Hu, E Dul, CM Sung, Z Chen, R Kirkpatrick… - … of Pharmacology and …, 2003 - ASPET
Histone deacetylases (HDACs) represent an expanding family of protein modifying-enzymes
that play important roles in cell proliferation, chromosome remodeling, and gene …
that play important roles in cell proliferation, chromosome remodeling, and gene …
[HTML][HTML] Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor
…, Z Chen, T Fredrickson, Y Zhu, R Kirkpatrick… - Journal of Biological …, 2000 - ASBMB
Histone acetylation alters chromatin state by modifying lysines on histone and plays an
important role in modulating gene transcription. A dynamic balance of histone acetylation/…
important role in modulating gene transcription. A dynamic balance of histone acetylation/…
Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-γ production
…, DJ Rieman, R Lehr, S Khandekar, RB Kirkpatrick… - Cytokine, 2002 - Elsevier
We have recently reported the identification of four novel members of the interleukin-1 (IL-1)
family which we designated as IL-1 homologue 1–4 (IL-1H1–4). These proteins exhibit …
family which we designated as IL-1 homologue 1–4 (IL-1H1–4). These proteins exhibit …
The negative influences of exam-oriented education on Chinese high school students: Backwash from classroom to child
R Kirkpatrick, Y Zang - Language testing in Asia, 2011 - Springer
This essay describes the various problems China faces on account of its exam-centric
education system and pedagogy. Along with interviews and focus groups, this study draws on …
education system and pedagogy. Along with interviews and focus groups, this study draws on …
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities
…, C Webb, S Khandekar, T Yi, R Kirkpatrick… - … of Pharmacology and …, 2007 - ASPET
Increased Rho kinase (ROCK) activity contributes to smooth muscle contraction and regulates
blood pressure homeostasis. We hypothesized that potent and selective ROCK inhibitors …
blood pressure homeostasis. We hypothesized that potent and selective ROCK inhibitors …
Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction
…, RH Sinnamon, H Zhang, RB Kirkpatrick… - Nature chemical …, 2014 - nature.com
Although therapeutic interventions of signal-transduction cascades with targeted kinase
inhibitors are a well-established strategy, drug-discovery efforts to identify targeted phosphatase …
inhibitors are a well-established strategy, drug-discovery efforts to identify targeted phosphatase …
Conifer defence against insects: microarray gene expression profiling of Sitka spruce (Picea sitchensis) induced by mechanical wounding or feeding by spruce …
…, YSN Butterfield, R Kirkpatrick… - Plant, Cell & …, 2006 - Wiley Online Library
Conifers are resistant to attack from a large number of potential herbivores or pathogens.
Previous molecular and biochemical characterization of selected conifer defence systems …
Previous molecular and biochemical characterization of selected conifer defence systems …