Microalbuminuria and endothelial dysfunction: emerging targets for primary prevention of end-organ damage
…, RH Henning, RPE van Dokkum… - Journal of …, 2006 - journals.lww.com
A minor increase in urinary albumin excretion (microalbuminuria) is known to predict adverse
renal and cardiovascular events in diabetic and hypertensive patients. Recent intriguing …
renal and cardiovascular events in diabetic and hypertensive patients. Recent intriguing …
Myocardial infarction enhances progressive renal damage in an experimental model for cardio-renal interaction
RPE van Dokkum, WBA Eijkelkamp… - Journal of the …, 2004 - journals.lww.com
Studied were the effects of myocardial infarction (MI) on mild renal function loss in unilateral
nephrectomized (UnX) rats. UnX was performed, followed after 1 wk by a variable MI (UnX+ …
nephrectomized (UnX) rats. UnX was performed, followed after 1 wk by a variable MI (UnX+ …
Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat
RPE van Dokkum, CW Sun… - American Journal …, 1999 - journals.physiology.org
The present study examined whether an abnormality in the myogenic response of renal
arterioles that impairs autoregulation of renal blood flow (RBF) and glomerular capillary …
arterioles that impairs autoregulation of renal blood flow (RBF) and glomerular capillary …
Endothelial dilatory function predicts individual susceptibility to renal damage in the 5/6 nephrectomized rat
…, D de Zeeuw, RPE van Dokkum - Journal of the …, 2002 - journals.lww.com
ABSTRACT. In experimental animal models of renal disease the degree of renal damage
varies between individuals. This could be caused by variation in the noxious event or by …
varies between individuals. This could be caused by variation in the noxious event or by …
Impaired autoregulation of renal blood flow in the fawn-hooded rat
RPE Van Dokkum, M Alonso-Galicia… - American Journal …, 1999 - journals.physiology.org
The responses to changes in renal perfusion pressure (RPP) were compared in 12-wk-old
fawn-hooded hypertensive (FHH), fawn-hooded low blood pressure (FHL), and August …
fawn-hooded hypertensive (FHH), fawn-hooded low blood pressure (FHL), and August …
Evidence of Gene—Gene Interactions in the Genetic Susceptibility to Renal Impairment after Unilateral Nephrectomy
…, AP Provoost, RPE VAN DOKKUM… - Journal of the …, 2000 - journals.lww.com
The number of patients with hypertension-associated end-stage renal failure (ESRF)
continues to increase despite improved antihypertensive management and early detection …
continues to increase despite improved antihypertensive management and early detection …
Effect of first myocardial ischemic event on renal function
…, DJ van Veldhuisen, RPE van Dokkum… - The American journal of …, 2007 - Elsevier
Effects of cardiovascular dysfunction on renal function have been poorly characterized.
Therefore, we investigated the relation between a first ischemic cardiac event and long-term …
Therefore, we investigated the relation between a first ischemic cardiac event and long-term …
Vildagliptin restores renal myogenic function and attenuates renal sclerosis independently of effects on blood glucose or proteinuria in Zucker diabetic fatty rat
…, LE Deelman, R PE van Dokkum… - Current Vascular …, 2014 - ingentaconnect.com
Type 2 diabetes mellitus (T2DM) is associated with risk for chronic kidney disease (CKD),
which is associated with a decrease in renal myogenic tone - part of renal autoregulatory …
which is associated with a decrease in renal myogenic tone - part of renal autoregulatory …
The role of angiotensin (1–7) in renal vasculature of the rat
…, P Ochodnický, RPE van Dokkum… - Journal of …, 2006 - journals.lww.com
Objective Angiotensin (1–7) is an active component of the renin–angiotensin–aldosterone
system. Its exact role in renal vascular function is unclear. We therefore studied the effects of …
system. Its exact role in renal vascular function is unclear. We therefore studied the effects of …
Myocardial infarction does not further impair renal damage in 5/6 nephrectomized rats
…, Y Xu, D de Zeeuw, RPE van Dokkum - Nephrology Dialysis …, 2008 - academic.oup.com
Background. Recent observational studies show that reduced renal function is an independent
risk factor for the development of cardiovascular disease. Previously, we reported that …
risk factor for the development of cardiovascular disease. Previously, we reported that …