User profiles for Richard A. Gillis

Richard Gillis

Verified email at georgetown.edu
Cited by 10032

Mechanism of the cardiotoxic actions of terfenadine

RL Woosley, Y Chen, JP Freiman, RA Gillis - Jama, 1993 - jamanetwork.com
Objectives and Methods. —To gain insight into possible mechanisms of and predisposing
factors for torsades de pointes during terfenadine therapy, spontaneous reports in the US …

Multidrug Efflux Pumps: Expression Patterns and Contribution to Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

TR De Kievit, MD Parkins, RJ Gillis… - Antimicrobial agents …, 2001 - Am Soc Microbiol
Pseudomonas aeruginosa biofilms are intrinsically resistant to antimicrobial chemotherapies.
At present, very little is known about the physiological changes that occur during the …

Genetic improvement of tomato by targeted control of fruit softening

…, R Smith, M Poole, G Adams, RB Gillis… - Nature …, 2016 - nature.com
Controlling the rate of softening to extend shelf life was a key target for researchers engineering
genetically modified (GM) tomatoes in the 1990s, but only modest improvements were …

Molecular Basis of Azithromycin-Resistant Pseudomonas aeruginosa Biofilms

RJ Gillis, KG White, KH Choi, VE Wagner… - Antimicrobial agents …, 2005 - Am Soc Microbiol
Pseudomonas aeruginosa biofilms are extremely recalcitrant to antibiotic treatment. Treatment
of cystic fibrosis patients with azithromycin (AZM) has shown promise. We used DNA …

Azithromycin Retards Pseudomonas aeruginosa Biofilm Formation

RJ Gillis, BH Iglewski - Journal of clinical microbiology, 2004 - Am Soc Microbiol
Using a flow cell biofilm model, we showed that a sub-MIC of azithromycin (AZM) can delay
but not inhibit Pseudomonas aeruginosa biofilm formation and results in the development of …

Basic fibroblast growth factor increases long-term survival of spinal motor neurons and improves respiratory function after experimental spinal cord injury

…, I Mocchetti, AM Taveira-DaSilva, RA Gillis… - Journal of …, 1999 - Soc Neuroscience
Acute focal injection of basic fibroblast growth factor (FGF2) protects ventral horn (VH)
neurons from death after experimental contusive spinal cord injury (SCI) at T8. Because these …

[HTML][HTML] The effectiveness of lifestyle adaptation for the prevention of prediabetes in adults: a systematic review

G Kerrison, RB Gillis, SI Jiwani, Q Alzahrani… - Journal of diabetes …, 2017 - hindawi.com
Diabetes prevalence is increasing exceptionally worldwide and with this come associated
healthcare costs. The primary outcome of this systematic review was to assess glycaemic …

The influence of surface features on bacterial colonization and subsequent substratum chemical changes of 316L stainless steel

GG Geesey, RJ Gillis, R Avci, D Daly, M Hamilton… - Corrosion …, 1996 - Elsevier
Biofilm-forming bacteria were found to selectively colonize specific surface features of
unpolished 316L stainless steel exposed to flowing aqueous media. Depending on the types of …

SEDFIT–MSTAR: molecular weight and molecular weight distribution analysis of polymers by sedimentation equilibrium in the ultracentrifuge

P Schuck, RB Gillis, TMD Besong, F Almutairi… - Analyst, 2014 - pubs.rsc.org
Sedimentation equilibrium (analytical ultracentrifugation) is one of the most inherently
suitable methods for the determination of average molecular weights and molecular weight …

Transcriptome analysis of quorum-sensing regulation and virulence factor expression in Pseudomonas aeruginosa

VE Wagner, RJ Gillis, BH Iglewski - Vaccine, 2004 - Elsevier
The opportunistic pathogen Pseudomonas aeruginosa possesses two well-studied quorum-sensing
(QS) systems (las and rhl) that are important in the production of virulence factors, …