Inhibition of MEK alone and in combination with ALK inhibition suppresses tumor growth in a mouse model of ALK positive lung cancer.

N Shrestha, AR Bland, RL Bower, R Rosengren… - … of Pharmacology and …, 2020 - ASPET
Anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer most commonly
arises through EML4-ALK chromosomal fusion. We have previously demonstrated that …

Evidence in Family Law Cases: A Bibliography, 2013-2018

L Bower - J. Am. Acad. Matrimonial Law., 2017 - HeinOnline
… Lauren BowerRebecca L. Scharf, Separated at Adoption: Addressing the Challenges
of Maintaining Sibling-of-Origin Bonds, in Post-Adoption … Rebecca Naeder, Note, "I Know …

A Bibliography, 2011-2017

L Bower - J. Am. Acad. Matrimonial Law., 2017 - HeinOnline
… Sam Halabi, The Hague Convention on the Civil Aspects of International Child Abduction
and the Latent Domestic Relations Exception to Federal Question Jurisdiction, 41 NCJ INT'L …

Customer power, strategic investment, and the failure of leading firms

CM Christensen, JL Bower - Strategic management journal, 1996 - Wiley Online Library
Why might firms be regarded as astutely managed at one point, yet subsequently lose their
positions of industry leadership when faced with technological change? We present a model, …

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance

…, M O'Donovan, A Miremadi, TP Yang, L Bower… - Nature …, 2016 - nature.com
Esophageal adenocarcinoma (EAC) has a poor outcome, and targeted therapy trials have
thus far been disappointing owing to a lack of robust stratification methods. Whole-genome …

[HTML][HTML] Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

…, J Gilbert, A Noorani, G Devonshire, L Bower… - Nature …, 2018 - nature.com
Esophageal adenocarcinoma (EAC) incidence is increasing while 5-year survival rates
remain less than 15%. A lack of experimental models has hampered progress. We have …

[HTML][HTML] A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

…, R Valdés-Mas, S Nakken, D Vodák, L Bower… - Nature …, 2015 - nature.com
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full
understanding of the variables affecting sequencing analysis output is required. Here using …

[BOOK][B] From resource allocation to strategy

JL Bower, CG Gilbert - 2005 - books.google.com
Joseph L. Bower and Clark G. Gilbert have collected together some of the leading experts
on strategy to examine how strategy is actually made by company managers across the …

The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic

…, G Contino, S Killcoyne, S Abbas, J Perner, L Bower… - Nature …, 2019 - nature.com
Esophageal adenocarcinoma (EAC) is a poor-prognosis cancer type with rapidly rising
incidence. Understanding of the genetic events driving EAC development is limited, and there …

Identification of subtypes of Barrett's esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and genome …

…, M Tripathi, AG Lynch, M Eldridge, M Secrier, L Bower… - Gastroenterology, 2020 - Elsevier
Background & Aims Esophageal adenocarcinomas (EACs) are heterogeneous and often
preceded by Barrett’s esophagus (BE). Many genomic changes have been associated with …