User profiles for R Masereeuw
Rosalinde MasereeuwProfessor of Experimental Pharmacology Verified email at uu.nl Cited by 13719 |
Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules
FGM Russel, JB Koenderink, R Masereeuw - Trends in pharmacological …, 2008 - cell.com
Multidrug resistance protein (MRP) 4 is a member of the MRP/ABCC subfamily of ATP-binding
cassette transporters, which are capable of pumping a wide variety of endogenous and …
cassette transporters, which are capable of pumping a wide variety of endogenous and …
Kidney-on-a-chip technology for drug-induced nephrotoxicity screening
Improved model systems to predict drug efficacy, interactions, and drug-induced kidney injury
(DIKI) are crucially needed in drug development. Organ-on-a-chip technology is a suitable …
(DIKI) are crucially needed in drug development. Organ-on-a-chip technology is a suitable …
Renal toxicity of radiolabeled peptides and antibody fragments: mechanisms, impact on radionuclide therapy, and strategies for prevention
…, M de Jong, JFM Wetzels, R Masereeuw… - Journal of nuclear …, 2010 - Soc Nuclear Med
Peptide-receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogs such
as octreotide is an effective therapy against neuroendocrine tumors. Other radiolabeled …
as octreotide is an effective therapy against neuroendocrine tumors. Other radiolabeled …
[HTML][HTML] The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane
…, S Heemskerk, FGM Russel, R Masereeuw - Kidney international, 2008 - Elsevier
The Breast Cancer Resistance Protein (BCRP/ABCG2) is a transporter restricting absorption
and enhancing excretion of many compounds including anticancer drugs. This transporter …
and enhancing excretion of many compounds including anticancer drugs. This transporter …
Tubuloids derived from human adult kidney and urine for personalized disease modeling
…, H Lanz, J Beekman, JL Murk, R Masereeuw… - Nature …, 2019 - nature.com
Adult stem cell-derived organoids are three-dimensional epithelial structures that
recapitulate fundamental aspects of their organ of origin. We describe conditions for the long-term …
recapitulate fundamental aspects of their organ of origin. We describe conditions for the long-term …
[HTML][HTML] Complexation-induced resolution enhancement of 3D-printed hydrogel constructs
…, H Wang, J Xie, M Yu, R Masereeuw… - Nature …, 2020 - nature.com
Three-dimensional (3D) hydrogel printing enables production of volumetric architectures
containing desired structures using programmed automation processes. Our study reports a …
containing desired structures using programmed automation processes. Our study reports a …
Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules
…, JGP Peters, FGM Russel, R Masereeuw - Drug metabolism and …, 2006 - ASPET
Different gene-silencing methods, like antisense and short interfering RNA (siRNA), are
widely used as experimental tools to inhibit gene expression. In the present study, the in vivo …
widely used as experimental tools to inhibit gene expression. In the present study, the in vivo …
[HTML][HTML] Ischemic preconditioning in the animal kidney, a systematic review and meta-analysis
…, JA van der Vliet, GA Rongen, R Masereeuw… - PloS one, 2012 - journals.plos.org
Ischemic preconditioning (IPC) is a potent renoprotective strategy which has not yet been
translated successfully into clinical practice, in spite of promising results in animal studies. We …
translated successfully into clinical practice, in spite of promising results in animal studies. We …
Molecular aspects of renal anionic drug transport
FGM Russel, R Masereeuw… - Annual review of …, 2002 - annualreviews.org
… Kooiman, R. Masereeuw & F. Russel, unpublished data) that encodes a gene product
including the conserved cysteine residue. Additional amino acid differences were also found, and …
including the conserved cysteine residue. Additional amino acid differences were also found, and …
[HTML][HTML] Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters
MJ Wilmer, MA Saleem, R Masereeuw, L Ni… - Cell and tissue …, 2010 - Springer
Reabsorption of filtered solutes from the glomerular filtrate and excretion of waste products
and xenobiotics are the main functions of the renal proximal tubular (PT) epithelium. A human …
and xenobiotics are the main functions of the renal proximal tubular (PT) epithelium. A human …