Mobilization of heavy metals by newer, therapeutically useful chelating agents
HV Aposhian, RM Maiorino, D Gonzalez-Ramirez… - Toxicology, 1995 - Elsevier
Four chelating agents that have been used most commonly for the treatment of humans
intoxicated with lead, mercury, arsenic or other heavy metals and metalloids are reviewed as to …
intoxicated with lead, mercury, arsenic or other heavy metals and metalloids are reviewed as to …
Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic
…, M Ma, L Yip, RA Zakharyan, RM Maiorino… - Chemical Research …, 2000 - ACS Publications
Monomethylarsonous acid (MMA III ) has been detected for the first time in the urine of some
humans exposed to inorganic arsenic in their drinking water. Our experiments have dealt …
humans exposed to inorganic arsenic in their drinking water. Our experiments have dealt …
DMPS–arsenic challenge test: II. Modulation of arsenic species, including monomethylarsonous acid (MMAIII), excreted in human urine
…, P Andrewes, L Yip, GF O'Malley, RM Maiorino… - Toxicology and Applied …, 2000 - Elsevier
The administration of sodium 2,3-dimercapto-1-propane sulfonate (DMPS) to humans
chronically exposed to inorganic arsenic in their drinking water resulted in the increased urinary …
chronically exposed to inorganic arsenic in their drinking water resulted in the increased urinary …
Human studies with the chelating agents, DMPS and DMSA
H Vasken Aposhian, RM Maiorino… - Journal of Toxicology …, 1992 - Taylor & Francis
Meso-2,3-dimercaptosuccinic acid (DMSA) is bound to plasma albumin in humans and appears
to be excreted in the urine as the DMSA-cysteine mixed disulfide. The pharmacokinetics …
to be excreted in the urine as the DMSA-cysteine mixed disulfide. The pharmacokinetics …
DMSA, DMPS, and DMPA—as arsenic antidotes
…, TD Hoover, CA Hsu, RM Maiorino… - Toxicological …, 1984 - academic.oup.com
… MAIORINO,* AND ERIC STTNEf … A., MAIORINO, RM, AND STTNE, E. (1984). Fundam. …
Sodium 2, 3-dimercaptopropane-1-sulfonate challenge test for mercury in humans: II. Urinary mercury, porphyrins and neurobehavioral changes of dental workers in …
D Gonzalez-Ramirez, RM Maiorino… - … of Pharmacology and …, 1995 - ASPET
The sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (DMPS) challenge test (300 mg
po after an 11-hr fast) was given in Monterrey, Mexico to dental and nondental personnel. …
po after an 11-hr fast) was given in Monterrey, Mexico to dental and nondental personnel. …
Determination and metabolism of dithiol chelating agents: VI. Isolation and identification of the mixed disulfides of meso-2, 3-dimercaptosuccinic acid with L-cysteine in …
RM Maiorino, DC Bruce, HV Aposhian - Toxicology and applied …, 1989 - Elsevier
Virtually nothing is known about the biotransformation of the heavy metal chelating agent,
meso-2,3-dimercaptosuccinic acid (DMSA). Two fasted, normal, young men wera given 10.0 …
meso-2,3-dimercaptosuccinic acid (DMSA). Two fasted, normal, young men wera given 10.0 …
Urinary excretion of meso‐2, 3‐dimercaptosuccinic acid in human subjects
HV Aposhian, RM Maiorino, RC Dart… - Clinical Pharmacology …, 1989 - Wiley Online Library
… A highly sensitive and accurate fluorescent method for the determination of dimercapto
compounds in the urine has been developed by Maiorino et al.2123 The method has made …
compounds in the urine has been developed by Maiorino et al.2123 The method has made …
Gas chromatographic determination of fentanyl and its analogues in human plasma
TJ Gillespie, AJ Gandolfi, RM Maiorino… - Journal of Analytical …, 1981 - academic.oup.com
There is currently no published chromatographic assay for the fentanyl family of analgesics.
This study reports the development of a sensitive, precise, and accurate gas …
This study reports the development of a sensitive, precise, and accurate gas …
Pharmacokinetics of meso-2, 3-dimercaptosuccinic acid in patients with lead poisoning and in healthy adults
RC Dart, KM Hurlbut, RM Maiorino, M Mayersohn… - The Journal of …, 1994 - Elsevier
We compared the pharmacokinetics of meso-2,3-dimercaptosuccinic acid (DMSA) in three
children with lead poisoning, three adults with lead poisoning, and five healthy adult …
children with lead poisoning, three adults with lead poisoning, and five healthy adult …