User profiles for R Higgs

Richard E Higgs

- Verified email at lilly.com - Cited by 7648

Rowan Higgs

- Verified email at tcd.ie - Cited by 3039

[HTML][HTML] Immunity to the respiratory pathogen Bordetella pertussis

R Higgs, SC Higgins, PJ Ross, KHG Mills - Mucosal immunology, 2012 - Elsevier
Bordetella pertussis causes whooping cough, a severe respiratory tract infection in infants
and children, and also infects adults. Studies in murine models have shown that innate …

Kinomics—structural biology and chemogenomics of kinase inhibitors and targets

M Vieth, RE Higgs, DH Robertson, M Shapiro… - … et Biophysica Acta (BBA …, 2004 - Elsevier
… This is further exemplified by the low R values (R=0.4, R 2 =0.16) in Table 3, where the SI is
… 5 for the LL group shows stronger correlation than all the groups taken together (R 2 =0.37, R

[HTML][HTML] Bamlanivimab plus etesevimab in mild or moderate Covid-19

…, TR Holzer, PJ Ebert, RE Higgs… - … England Journal of …, 2021 - Mass Medical Soc
Background Patients with underlying medical conditions are at increased risk for severe
coronavirus disease 2019 (Covid-19). Whereas vaccine-derived immunity develops over time, …

Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial

…, G Oakley, AE Schade, TR Holzer, PJ Ebert, RE Higgs… - Jama, 2021 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) continues to spread rapidly worldwide.
Neutralizing antibodies are a potential treatment for COVID-19. Objective To determine the …

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

…, BA Heinz, D Foster, RE Higgs… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat
for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies …

[PDF][PDF] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

…, RE Higgs, NL Kallewaard, K Jepson, R Goya… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (…

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides

…, XIN Wu, M Esterman, D Koger, J Hanson, R Higgs… - Nature medicine, 2004 - nature.com
We have previously shown that apolipoprotein E (Apoe) promotes the formation of amyloid
in brain and that astrocyte-specific expression of APOE markedly affects the deposition of …

Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease?

C Jefferies, C Wynne, R Higgs - Nature Reviews Immunology, 2011 - nature.com
The concept that viral sensing systems, via their ability to drive pro-inflammatory cytokine and
interferon production, contribute to the development of autoimmune and autoinflammatory …

[BOOK][B] Competition and coercion: Blacks in the American economy 1865-1914

R Higgs - 1977 - books.google.com
… Professor Higgs's account is iconoclastic. It seeks to reorganize the present conceptualization
of the period and to redirect future study of black economic history in the post-Emanipation …

Changing face of medical curricula

R Jones, R Higgs, C De Angelis, D Prideaux - The Lancet, 2001 - thelancet.com
The changing role of medicine in society and the growing expectations patients have of their
doctors means that the content and delivery of medical curricula also have to change. The …