Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

…, SY Wang, K Zheng, LC Lei, QX Chen… - Proceedings of the …, 2005 - National Acad Sciences
The genomic sequences of severe acute respiratory syndrome coronaviruses from human
and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly …

Quasi-min–max MPC for constrained nonlinear systems with guaranteed input-to-state stability

DF He, H Huang, QX Chen - Journal of the Franklin Institute, 2014 - Elsevier
This paper presents a robust quasi-min–max model predictive control algorithm for a class
of nonlinear systems described by linear parameter varying (LPV) systems subject to input …

[HTML][HTML] A review on human body communication: Signal propagation model, communication performance, and experimental issues

JF Zhao, XM Chen, BD Liang, QX Chen - … and Mobile Computing, 2017 - hindawi.com
… Xi Mei Chen designed and carried out the experiments, analyzed the data, and drafted the
manuscript. Bo Dong Liang helped to collect the data and draft the manuscript. Qiu Xia Chen

A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications

QX Chen, WP Wang, S Zeng, S Urayama… - Nucleic acids …, 2015 - academic.oup.com
RNA research and therapy relies primarily on synthetic RNAs. We employed recombinant
RNA technology toward large-scale production of pre-miRNA agents in bacteria, but found the …

Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth

Y Zhao, MJ Tu, YF Yu, WP Wang, QX Chen… - Biochemical …, 2015 - Elsevier
Osteosarcoma (OS) is the most common form of primary malignant bone tumor and prevalent
among children and young adults. Recently we have established a novel approach to …

Bioengineering novel chimeric microRNA-34a for prodrug cancer therapy: high-yield expression and purification, and structural and functional characterization

WP Wang, PY Ho, QX Chen, B Addepalli… - … of Pharmacology and …, 2015 - ASPET
Development of anticancer treatments based on microRNA (miRNA/miR) such as miR-34a
replacement therapy is limited to the use of synthetic RNAs with artificial modifications. Herein…

Chimeric microRNA-1291 biosynthesized efficiently in Escherichia coli is effective to reduce target gene expression in human carcinoma cells and improve …

MM Li, B Addepalli, MJ Tu, QX Chen, WP Wang… - Drug Metabolism and …, 2015 - ASPET
In contrast to the growing interests in studying noncoding RNAs (ncRNAs) such as microRNA
(miRNA or miR) pharmacoepigenetics, there is a lack of efficient means to cost effectively …

Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo

QY Zhang, PY Ho, MJ Tu, JL Jilek, QX Chen… - International journal of …, 2018 - Elsevier
Recently we have established a novel approach to produce bioengineered noncoding RNA
agents (BERAs) in living cells that carry target RNAi molecules (eg, siRNA and miRNA) and …

[HTML][HTML] Nutrient Uptake and Utilization by Fragrant Rosewood (Dalbergia odorifera) Seedlings Cultured with Oligosaccharide Addition under Different Lighting …

XW Li, QX Chen, HQ Lei, JW Wang, S Yang, HX Wei - Forests, 2018 - mdpi.com
Fragrant rosewood (Dalbergia odorifera TC Chen) is a highly-valued species suffering from
vulnerability due to over-development for wood and medicine. In this study, Fragrant …

CYP2C9* 3 (1075A> C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics

Q Zhou, Q Chen, Z Ruan, H Yuan… - Die Pharmazie-An …, 2013 - ingentaconnect.com
… Author contribution Quan zHOU, Zou-rong RUAN and Su zENG conceived and designed
research; Quan zHOU and Hong YUAN analyzed clinical samples; Qiu-xia CHEN and Hui-min …