Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo [a] pyrene plus 4-(methylnitrosamino)-1-(3 …
…, M Wang, N Trushin, S Agarwal, AV Rao, P Upadhyaya - Cancer letters, 1999 - Elsevier
The potential activities of butylated hydroxyanisole (BHA), myo-inositol, curcumin, esculetin,
resveratrol and lycopene-enriched tomato oleoresin (LTO) as chemopreventive agents …
resveratrol and lycopene-enriched tomato oleoresin (LTO) as chemopreventive agents …
Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4 …
S Kalscheuer, X Zhang, Y Zeng, P Upadhyaya - Carcinogenesis, 2008 - academic.oup.com
While numerous microRNAs (miRNAs) have been reported to alter their expression levels
in human lung cancer tissues compared with normal tissues, the function of these miRNAs …
in human lung cancer tissues compared with normal tissues, the function of these miRNAs …
[HTML][HTML] Transport of the β-O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug …
EM Leslie, K Ito, P Upadhyaya, SS Hecht… - Journal of Biological …, 2001 - ASBMB
Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
(NNAL) play a crucial role in the induction of lung …
(NNAL) play a crucial role in the induction of lung …
Research on cruciferous vegetables, indole‐3‐carbinol, and cancer prevention: A tribute to Lee W. Wattenberg
N Fujioka, V Fritz, P Upadhyaya… - Molecular nutrition & …, 2016 - Wiley Online Library
Lee W. Wattenberg, who spent his entire career at the University of Minnesota, was a true
pioneer in the field of chemoprevention. This paper is a tribute to his groundbreaking research …
pioneer in the field of chemoprevention. This paper is a tribute to his groundbreaking research …
Clinical trial of 2-phenethyl isothiocyanate as an inhibitor of metabolic activation of a tobacco-specific lung carcinogen in cigarette smokers
…, L Strayer, J Adams-Haduch, P Upadhyaya… - Cancer prevention …, 2016 - AACR
2-Phenethyl isothiocyanate (PEITC), a natural product found as a conjugate in watercress
and other cruciferous vegetables, is an inhibitor of the metabolic activation and lung …
and other cruciferous vegetables, is an inhibitor of the metabolic activation and lung …
Application of a high-resolution mass-spectrometry-based DNA adductomics approach for identification of DNA adducts in complex mixtures
S Balbo, SS Hecht, P Upadhyaya… - Analytical chemistry, 2014 - ACS Publications
Liquid chromatography coupled with mass spectrometry (LC-MS) is the method of choice for
analysis of covalent modification of DNA. DNA adductomics is an extension of this approach …
analysis of covalent modification of DNA. DNA adductomics is an extension of this approach …
Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated …
…, EJ McIntee, PW Villalta, P Upadhyaya… - Chemical research in …, 2003 - ACS Publications
The tobacco specific carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
and N‘-nitrosonornicotine (NNN) are metabolically activated to 4-oxo-4-(3-pyridyl)-1-…
and N‘-nitrosonornicotine (NNN) are metabolically activated to 4-oxo-4-(3-pyridyl)-1-…
Inhibition of 7,12-Dimethylbenz(a)anthracene-induced Tumors and DNA Adduct Formation in the Mammary Glands of Female Sprague-Dawley Rats by the Synthetic …
K El-Bayoumy, YH Chae, P Upadhyaya, C Meschter… - Cancer research, 1992 - AACR
We synthesized a novel organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate
(XSC), possessing low toxicity by comparison with inorganic Na 2 SeO 3 , and several …
(XSC), possessing low toxicity by comparison with inorganic Na 2 SeO 3 , and several …
Comparison of the effects of an organic and an inorganic form of selenium on a mammary carcinoma cell line
The development of new compounds with greater cancer inhibitory activity and that are well
tolerated continues to be a priority in chemoprevention research involving selenium. One …
tolerated continues to be a priority in chemoprevention research involving selenium. One …
Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats
K El-Bayoumy, YH Chae, P Upadhyaya… - …, 1995 - academic.oup.com
Agents that are ubiquitous in the environment and are known inducers of mammary cancer
in rodents can be regarded as potential causes of human cancer and need to be evaluated …
in rodents can be regarded as potential causes of human cancer and need to be evaluated …