[HTML][HTML] Estrogen receptors and endometriosis
…, A Weyl, K Vergriete, E Buscail, P Lluel… - International journal of …, 2020 - mdpi.com
Endometriosis is a frequent and chronic inflammatory disease with impacts on reproduction,
health and quality of life. This disorder is highly estrogen-dependent and the purpose of …
health and quality of life. This disorder is highly estrogen-dependent and the purpose of …
[HTML][HTML] Characterization of human colon organoids from inflammatory bowel disease patients
…, G Portier, JP Duffas, S Chabot, P Lluel… - Frontiers in cell and …, 2020 - frontiersin.org
Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial
defects drive, at least in part, some of the pathology. We reconstituted human intestinal …
defects drive, at least in part, some of the pathology. We reconstituted human intestinal …
Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder
…, D Desoubzdanne, B Corman, S Palea, P Lluel… - European journal of …, 2013 - Elsevier
This work aimed at establishing the relevance of using the in vivo model of cyclophosphamide
(CYP)-induced bladder inflammation in rats for in vivo pharmacological studies. …
(CYP)-induced bladder inflammation in rats for in vivo pharmacological studies. …
[HTML][HTML] Characterization and validation of a chronic model of cyclophosphamide-induced interstitial cystitis/bladder pain syndrome in rats
C Augé, X Gamé, N Vergnolle, P Lluel… - Frontiers in …, 2020 - frontiersin.org
Interstitial cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic inflammatory disease
characterized by visceral pain and voiding symptoms. IC/BPS is still an unsolved enigma with …
characterized by visceral pain and voiding symptoms. IC/BPS is still an unsolved enigma with …
Modulation of non‐voiding activity by the muscarinergic antagonist tolterodine and the β3‐adrenoceptor agonist mirabegron in conscious rats with partial outflow …
…, S Palea, V Guilloteau, M Guerard, P Lluel… - BJU …, 2012 - Wiley Online Library
… Stefano Palea, Veronique Guilloteau, Marc Guerard and Philippe Lluel are Study
Investigators on project paid by Sponsor. Source of funding: Astellas Pharma Europe BV …
Investigators on project paid by Sponsor. Source of funding: Astellas Pharma Europe BV …
[HTML][HTML] A new tumorgraft panel to accelerate precision medicine in prostate cancer
…, J Masliah-Planchon, E Potiron, P Lluel… - Frontiers in …, 2023 - frontiersin.org
BACKGROUND Despite the significant advances in the management of advanced prostate
cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in …
cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in …
Comparative effect of alfuzosin and tamsulosin on the contractile response of isolated rabbit prostatic and iris dilator smooth muscles: possible model for intraoperative …
…, DF Chang, M Rekik, A Regnier, P Lluel - Journal of Cataract & …, 2008 - Elsevier
PURPOSE: To compare the pharmacologic properties of tamsulosin and alfuzosin in isolated
prostatic and iris dilator smooth muscle from pigmented rabbits. SETTING: UROsphere …
prostatic and iris dilator smooth muscle from pigmented rabbits. SETTING: UROsphere …
G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors
At a time when pharmaceutical companies are having trouble finding new low MW drugs
and when biologics are becoming more common, animal venoms could constitute an …
and when biologics are becoming more common, animal venoms could constitute an …
OBE022, an oral and selective prostaglandin F2α receptor antagonist as an effective and safe modality for the treatment of preterm labor
…, F Spézia, F Gervais, P Guillaume, P Lluel… - … of Pharmacology and …, 2018 - ASPET
Preterm birth is the major challenge in obstetrics, affecting ∼10% of pregnancies. Pan-prostaglandin
synthesis inhibitors [nonsteroidal anti-inflammatory drugs (NSAIDs)] prevent …
synthesis inhibitors [nonsteroidal anti-inflammatory drugs (NSAIDs)] prevent …
Experimental bladder instability following bladder outlet obstruction in the female rat
P LLUEL, C DUQUENNE, D MARTIN - The Journal of urology, 1998 - Elsevier
PURPOSE: In rats, urethral obstruction was previously shown to lead to detrusor instability,
but bladder instability in conscious animals has not been well characterized. The present …
but bladder instability in conscious animals has not been well characterized. The present …