Nigral glutathione deficiency is not specific for idiopathic Parkinson's disease

PS Fitzmaurice, L Ang, M Guttman… - … : official journal of the …, 2003 - Wiley Online Library
The consistent findings of decreased levels of the major antioxidant glutathione in substantia
nigra of patients with idiopathic Parkinson's disease (PD) has provided most of the basis for …

Brain serotonin transporter in human methamphetamine users

SJ Kish, PS Fitzmaurice, I Boileau, GA Schmunk… - …, 2009 - Springer
Rationale Research on methamphetamine (MA) toxicity primarily focuses on the possibility
that some of the behavioural problems in human MA users might be caused by damage to …

Levels of 4-hydroxynonenal and malondialdehyde are increased in brain of human chronic users of methamphetamine

PS Fitzmaurice, J Tong, M Yazdanpanah, PP Liu… - … of Pharmacology and …, 2006 - ASPET
Animal studies suggest that the widely used psychostimulant drug methamphetamine (MA)
can harm brain dopamine neurones, possibly by causing oxidative damage. However, …

Effect of D1-like and D2-like receptor antagonists on methamphetamine and 3, 4-methylenedioxymethamphetamine self-administration in rats

…, RA Lea, PS Fitzmaurice, S Schenk - Behavioural …, 2009 - journals.lww.com
It has been suggested that activation of dopamine D1-like and D2-like receptors contribute
equally to the maintenance of drug self-administration. This study compared the contribution …

Do glutathione levels decline in aging human brain?

J Tong, PS Fitzmaurice, A Moszczynska… - Free Radical Biology …, 2016 - Elsevier
… Author links open overlay panel Junchao Tong a b , Paul S. Fitzmaurice c , Anna Moszczynska
d , Katie Mattina a b , Lee-Cyn Ang e , Isabelle Boileau b , Yoshiaki Furukawa f , Napapon …

Chemical and physical variations of cannabis smoke from a variety of cannabis samples in New Zealand

…, HJ Hamnett, R Beasley, PS Fitzmaurice - Forensic sciences …, 2019 - academic.oup.com
Studies have compared the chemical properties of tobacco smoke to those of cannabis
smoke, with the objective of identifying the chemical attributes responsible for the mutagenicity …

Benzylpiperazine: a drug of abuse?

…, MA Kennedy, PS Fitzmaurice - Journal of …, 2007 - journals.sagepub.com
… In NZ a Government ruling retained BZP’s legal status despite ongoing parliamentary
and public debate on the safety of BZP pills. In order to allow for the controlled sale of BZP-based …

Methamphetamine self-administration and the effect of contingency on monoamine and metabolite tissue levels in the rat

…, C Carati, RA Lea, PS Fitzmaurice, S Schenk - Brain research, 2010 - Elsevier
A number of studies have shown that exposure to high doses of methamphetamine (MA) is
toxic to central dopamine (DA) and serotonin (5-HT) neurons. In most of those studies, …

Brain dopamine‐stimulated adenylyl cyclase activity in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy

J Tong, PS Fitzmaurice, LC Ang… - Annals of Neurology …, 2004 - Wiley Online Library
The dopamine D 1 receptor is considered to participate in levodopa's antiparkinsonian action
and levodopa‐induced dyskinesias. We examined the functional status of the D 1 receptor …

N-benzylpiperazine has characteristics of a drug of abuse

…, PS Fitzmaurice, RA Lea, S Schenk - Behavioural …, 2007 - journals.lww.com
The ability of benzylpiperazine (BZP) to substitute for cocaine and to initiate self-administration
in drug-naive subjects was assessed to determine whether BZP has abuse liability. …