Purinergic receptors influence the differentiation of human mesenchymal stem cells
N Zippel, CA Limbach, N Ratajski, C Urban… - Stem cells and …, 2012 - liebertpub.com
Adult stem cells, including adipose tissue-derived mesenchymal stem cells (MSCs) or
ectomesenchymal dental follicle cells (DFCs), attract considerable attention for their potential to …
ectomesenchymal dental follicle cells (DFCs), attract considerable attention for their potential to …
MicroRNA-223 antagonizes angiogenesis by targeting β1 integrin and preventing growth factor signaling in endothelial cells
L Shi, B Fisslthaler, N Zippel, T Frömel, J Hu… - Circulation …, 2013 - Am Heart Assoc
Rationale: Endothelial cells in situ are largely quiescent, and their isolation and culture are
associated with the switch to a proliferative phenotype. Objective: To identify antiangiogenic …
associated with the switch to a proliferative phenotype. Objective: To identify antiangiogenic …
Biomaterials and mesenchymal stem cells for regenerative medicine
N Zippel, M Schulze, E Tobiasch - Recent patents on …, 2010 - ingentaconnect.com
The reconstruction of hard and soft tissues is a major challenge in regenerative medicine,
since diseases or traumas are causing increasing numbers of tissue defects due to the aging …
since diseases or traumas are causing increasing numbers of tissue defects due to the aging …
Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis
…, N Mangels, R Abdel Malik, N Zippel… - Cardiovascular …, 2015 - academic.oup.com
Aims Secreted modular calcium-binding protein 1 (SMOC1) is a matricellular protein that
potentially interferes with growth factor receptor signalling. The aim of this study was to …
potentially interferes with growth factor receptor signalling. The aim of this study was to …
AMP-activated protein kinase α2 in neutrophils regulates vascular repair via hypoxia-inducible factor-1α and a network of proteins affecting metabolism and apoptosis
R Abdel Malik, N Zippel, T Frömel, J Heidler… - Circulation …, 2017 - Am Heart Assoc
Rationale: The AMP-activated protein kinase (AMPK) is stimulated by hypoxia, and although
the AMPKα1 catalytic subunit has been implicated in angiogenesis, little is known about the …
the AMPKα1 catalytic subunit has been implicated in angiogenesis, little is known about the …
Transforming growth factor-β–activated kinase 1 regulates angiogenesis via AMP-activated protein kinase-α1 and redox balance in endothelial cells
N Zippel, RA Malik, T Frömel, R Popp… - … , and vascular biology, 2013 - Am Heart Assoc
Objective— Transforming growth factor-β–activated kinase 1 (TAK1) is a mitogen-activated
protein 3-kinase and an AMP-activated protein kinase (AMPK) kinase in some cell types. …
protein 3-kinase and an AMP-activated protein kinase (AMPK) kinase in some cell types. …
[HTML][HTML] Characterization and validation of in vitro and in vivo models to investigate TNF-α-induced inflammation in retinal diseases
CM Weigelt, N Zippel, H Fuchs… - … Vision Science & …, 2022 - iovs.arvojournals.org
Purpose: Inflammation is implicated in the etiology of diverse retinopathies including uveitis,
age-related macular degeneration or diabetic retinopathy. Tumor necrosis factor alpha (TNF-…
age-related macular degeneration or diabetic retinopathy. Tumor necrosis factor alpha (TNF-…
[HTML][HTML] Endothelial AMP-activated kinase α1 phosphorylates eNOS on Thr495 and decreases endothelial NO formation
N Zippel, AE Loot, H Stingl… - International journal of …, 2018 - mdpi.com
AMP-activated protein kinase (AMPK) is frequently reported to phosphorylate Ser1177 of
the endothelial nitric-oxide synthase (eNOS), and therefore, is linked with a relaxing effect. …
the endothelial nitric-oxide synthase (eNOS), and therefore, is linked with a relaxing effect. …
[HTML][HTML] Sema3A antibody BI-X prevents cell permeability and cytoskeletal collapse in HRMECs and increases tip cell density in mouse oxygen-induced retinopathy
N Zippel, CH Kenny, H Wu, M Garneau… - … Vision Science & …, 2022 - tvst.arvojournals.org
Purpose: Semaphorin 3A (Sema3A) is an axonal guidance molecule that inhibits
angiogenesis by vasorepulsion and blocks revascularization in the ischemic retina. BI-X is an …
angiogenesis by vasorepulsion and blocks revascularization in the ischemic retina. BI-X is an …
Human dental follicle precursor cells of wisdom teeth: isolation and differentiation towards osteoblasts for implants with and without scaffolds
EM Haddouti, M Skroch, N Zippel… - Materialwissenschaft …, 2009 - Wiley Online Library
The human dental follicle is a developmental precursor for essential periodontal tissues such
as periodontal ligament and root development. These cells can be expected to differentiate …
as periodontal ligament and root development. These cells can be expected to differentiate …