Coexpression of corticotropin-releasing hormone and urotensin i precursor genes in the caudal neurosecretory system of the euryhaline flounder (Platichthys flesus) …

W Lu, L Dow, S Gumusgoz, MJ Brierley… - …, 2004 - academic.oup.com
CRH and urotensin I (UI) are neuroendocrine peptides that belong to the superfamily of
corticotropin-releasing factors. In mammals, these peptides regulate the stress response and …

Molecular Characterization and Expression of Urotensin II and its Receptor in the Flounder (Platichthys flesus): A Hormone System Supporting Body Fluid …

…, L Dow, J Yuill, J Worthington, MJ Brierley… - …, 2006 - academic.oup.com
Urotensin II (UII) is a potent vasoconstrictor in mammals, but the source of circulating UII
remains unclear. Investigations of the caudal neurosecretory system (CNSS), considered the …

Fish caudal neurosecretory system: a model for the study of neuroendocrine secretion

CR McCrohan, W Lu, MJ Brierley, L Dow… - General and comparative …, 2007 - Elsevier
The caudal neurosecretory system (CNSS) is unique to fish and has suggested homeostatic
roles in osmoregulation and reproduction. Magnocellular neuroendocrine Dahlgren cells, …

Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine …

K Strømgaard, MJ Brierley, K Andersen… - Journal of medicinal …, 1999 - ACS Publications
Philanthotoxin-433 (PhTX-433), a natural polyamine wasp toxin, is a noncompetitive antagonist
of certain ionotropic receptors. Six analogues of PhTX-343 (a synthetic analogue of the …

Potentiation and inhibition of nicotinic acetylcholine receptors by spermine in the TE671 human muscle cell line

Z Shao, IR Mellor, MJ Brierley, J Harris… - … of Pharmacology and …, 1998 - ASPET
Nicotinic acetylcholine receptors (nAChR) of the TE671 cell line were investigated using
whole-cell and membrane patch recording techniques. At negative holding potentials (V H ), …

Bayesian estimation of migration flows

MJ Brierley, JJ Forster, JW McDonald… - … Migration in Europe …, 2008 - books.google.com
In this chapter, we explore a Bayesian modelling framework for generating estimates of
place-to-place migration flows. The framework is designed to offer a flexible approach which is …

Behavioral Function of Glutamatergic Interneurons in the Feeding System of Lymnaea: Plateauing Properties and Synaptic Connections with Motor Neurons

MJ Brierley, K Staras… - Journal of …, 1997 - journals.physiology.org
Brierley, Matthew J., Kevin Staras, and Paul R. Benjamin. Behavioral function of glutamatergic
interneurons in the feeding system of Lymnaea: plateauing properties and synaptic …

[HTML][HTML] Functional expression of a recombinant unitary glutamate receptor from Xenopus, which contains N-methyl-D-aspartate (NMDA) and non-NMDA receptor …

MM Soloviev, MJ Brierley, ZY Shao, IR Mellor… - Journal of biological …, 1996 - ASBMB
A cDNA encoding a 100-kDa subunit (XenNR1) of the N-methyl-D-aspartate (NMDA) glutamate
receptor type has been cloned from Xenopus central nervous system. When XenNR1 is …

Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors

…, DB Tikhonov, I Neagoe, Z Shao, MJ Brierley… - Molecular …, 2003 - ASPET
Whole-cell recordings and outside-out patch recordings from TE671 cells were made to
investigate antagonism of human muscle nicotinic acetylcholine receptors (nAChR) by the …

Solid phase synthesis and biological evaluation of enantiomerically pure wasp toxin analogues PhTX‐343 and PhTX‐12

…, I Bjørnsdottir, K Andersen, MJ Brierley… - Chirality: The …, 2000 - Wiley Online Library
PhTX‐343 and PhTX‐12, analogues of the natural polyamine wasp toxin PhTX‐433, were
synthesised in 40–60% yields as pure enantiomers using solid phase synthesis techniques. …