Stearoyl–CoA desaturase (SCD) is a central lipogenic enzyme catalyzing the synthesis of
monounsaturated fatty acids, mainly oleate (C18:1) and palmitoleate (C16:1), which are …

Leptin elicits a metabolic response that cannot be explained by its anorectic effects alone.
To examine the mechanism underlying leptin's metabolic actions, we used transcription …

Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme catalyzing the synthesis of
monounsaturated fatty acids, mainly oleate (18:1) and palmitoleate (16:1). These represent the …

Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the biosynthesis of
oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane …

Stearoyl-CoA desaturase (SCD) is expressed at high levels in several human tissues and is
required for the biosynthesis of oleate (18:1) and palmitoleate (16:1). These …

Stearoyl-CoA desaturase (SCD) catalyzes the rate-limiting step in the biosynthesis of
monounsaturated fatty acids. Mice with a targeted disruption of the SCD1 isoform have reduced …

Stearoyl-CoA desaturase-1 (SCD1), a critical regulator of energy metabolism, catalyzes the
synthesis of monounsaturated fats. To understand the tissue-specific role of SCD1 in energy …

Obesity and type 2 diabetes are strongly associated with abnormal lipid metabolism and
accumulation of intramyocellular triacylglycerol, but the underlying cause of these perturbations …

Stearoyl-CoA desaturase (SCD) (EC 1.14.99.5) is an endoplasmic reticulum-bound enzyme
that catalyzes the Δ9-cis desaturation of saturated fatty acyl-CoAs, the preferred substrates …

Stearoyl-CoA desaturase (SCD) synthesizes oleate necessary for the biosynthesis of
triglycerides and other lipids. Mice with a targeted disruption of the SCD1 gene are deficient in …