The authors conducted a double-blind, placebo-controlled study of the effect of lithium on
aggressive behavior. The 66 subjects, who were prisoners in a medium security institution, …

Units in areas of the midbrain rich in neurons containing serotonin respond to parenteral
injections of d-lysergic acid diethylamide by a reversible cessation of spontaneous activity. The …

: Plasma testosterone was determined in 36 male prisoners; 12 with chronic aggressive
behavior, 12 socially dominant without physical aggressiveness and 12 who were not physically …

… SHEARD, MD t Ilithium has become a widely accepted treatment … Sheard, MH Behavioral
effects of p-chlorophenylalanine; … Sheard, MH Effect of lithium on foot shock aggression in rats. …

Because of the previous observation that D-lysergic acid diethylamide (LSD) inhibits raphe
neurons, the possible effects on raphe units of other psychotogenic drugs were investigated. …

LITHIUM has been shown to be effective in the manic and hypomanic phase of manic-depressive
psychosis 1–3 , and to some extent to prevent manic episodes and, to a lesser degree, …

Monoamine oxidase inhibitors were administered to rats while the activities of single,
serotonin-containing neurons of the midbrain raphe nuclei were being monitored with …

… AND MH SHEARD. Habituation and sensitization of the rat startle response: effects of raphe
… United States Public Health Service Grants MH-17856 and MH-07114, by National Science …

… 6 Hydroxydopa depletion of brain norepinephrine and the facilitation of aggressive behavior
Science 1972; 17875-7 Sheard MH, Aggressive behavior: effects neural modulation by …

Electrical stimulation of the midbrain raphé, an area in which neuronal perikarya containing
serotonin are aggregated, produces an increase in 5-hydroxyindoleacetic acid and a …