A 200–300 kb region of chromosome 3p14.2, including the fragile site locus FRA3B, is
homozygously deleted in multiple tumor-derived cell lines. Exon amplification from cosmids …

To determine the role of the FHIT gene, which encompasses the fragile site at 3p14.2, we
analyzed 59 tumors of the small cell and non-small cell type by reverse transcription of FHIT …

Friedreich ataxia (FRDA) is a progressive neuro- and cardio-degenerative disorder characterized
by ataxia, sensory loss, and hypertrophic cardiomyopathy. In most cases, the disorder …

The FHIT gene, encoded by 10 exons in a 1.1-kb transcript, encompasses approximately 1
Mb of genomic DNA, which includes the hereditary RCC t(3;8) translocation break at 3p14.2, …

Friedreich ataxia is an autosomal recessive, inherited neuro- and cardio-degenerative disorder
characterized by progressive ataxia of all four limbs, dysarthria, areflexia, sensory loss, …

This study tested the ability of A0001 (α‐tocopheryl quinone; EPI‐A0001), a potent antioxidant,
to improve in vitro measures, glucose metabolism, and neurological function in Friedreich …

Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused
by a triplet guanine-adenine-adenine (GAA) repeat expansion in intron 1 of the FXN gene, …

A number of DNA fragments, identified by representational difference analysis, which were
homozygously deleted in various cancer cell lines were previously mapped to human …

A pharmacokinetic analysis of CDPcholine has been carried out treating either rats or dogs
by oral administration with the double labelled molecule. [methyl- 14 C,5- 3 H]CDPcholine …

Friedreich ataxia, the most common hereditary ataxia, is a neuro- and cardio-degenerative
disorder caused, in most cases, by decreased expression of the mitochondrial protein frataxin…