Human α-synuclein overexpression and its toxic accumulation in neurons or glia are known
to play key roles in the pathogenesis of Parkinson's disease and other related …

Abstract Effects of silencing ectopically expressed hSNCA in rat substantia nigra (SN) were
examined as a novel therapeutic approach to Parkinson's disease (PD). AAV-hSNCA with or …

Distributive shock is a subset of shock marked by decreased systemic vascular resistance,
organ hypoperfusion and altered oxygen extraction. Despite the use of intravenous fluids and …

Alpha-synuclein (SNCA), an abundantly expressed presynaptic protein, is implicated in
Parkinson's disease (PD). Since over-expression of human SNCA (hSNCA) leads to death of …

Serum dopamine‐β‐hydroxylase (DBH) activity was determined in male adult psychiatric
patients (n ‐ 280) and age‐matched male healthy controls (n= 100). Patients included in the …

At the neuromuscular synapse, innervation induces endplate-specific expression of adult-type
nicotinic acetylcholine receptors by selective expression of their subunit-encoding genes (…

Acute ethanol treatment of NG108-15 neuroblastoma x glioma hybrid cells results in
inhibition of adenosine uptake with consequent increases in extracellular adenosine and …

An Ets transcription factor family member, GETS-1, was cloned from a goldfish retina cDNA
library. GETS-1 contains a conserved Ets DNA-binding domain at its N-terminus and is most …

We have identified a negative cis-acting regulatory element in the nicotinic acetylcholine
receptor δ-subunit gene's promoter. This element resides within a previously identified 47-base …

The method is based on the formation of protein-phosphomolybdate complex in relatively mild
acidic conditions in the presence of a non-ionic detergent and low molybdate content. The …