User profiles for Lora D. Weidner
Lora D. WeidnerKarolinska Institutet Verified email at ki.se Cited by 355 |
The inhibitor Ko143 is not specific for ABCG2
LD Weidner, SS Zoghbi, S Lu, S Shukla… - … of Pharmacology and …, 2015 - ASPET
Imaging ATP-binding cassette (ABC) transporter activity in vivo with positron emission
tomography requires both a substrate and a transporter inhibitor. However, for ABCG2, there is no …
tomography requires both a substrate and a transporter inhibitor. However, for ABCG2, there is no …
Tariquidar is an inhibitor and not a substrate of human and mouse P-glycoprotein
Since its development, tariquidar (TQR; XR9576; N-[2-[[4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide) …
The expression of inflammatory markers and their potential influence on efflux transporters in drug‐resistant mesial temporal lobe epilepsy tissue
Objective The role of neuroinflammation in mesial temporal lobe epilepsy ( MTLE ), and
how it relates to drug resistance, remains unclear. Expression levels of the inflammatory …
how it relates to drug resistance, remains unclear. Expression levels of the inflammatory …
Quantitative Brain Amyloid PET
…, DM Krainak, SJ Wang, LD Weidner… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Since the development of amyloid tracers for PET imaging, there has been interest in quantifying
amyloid burden in the brains of patients with Alzheimer disease. Quantitative amyloid …
amyloid burden in the brains of patients with Alzheimer disease. Quantitative amyloid …
PET Imaging of Phosphodiesterase-4 Identifies Affected Dysplastic Bone in McCune–Albright Syndrome, a Genetic Mosaic Disorder
LD Weidner, Y Wakabayashi, LA Stolz… - Journal of Nuclear …, 2020 - Soc Nuclear Med
McCune–Albright syndrome (MAS) is a mosaic disorder arising from gain-of-function
mutations in the GNAS gene, which encodes the 3′,5′-cyclic adenosine monophosphate (cAMP) …
mutations in the GNAS gene, which encodes the 3′,5′-cyclic adenosine monophosphate (cAMP) …
[HTML][HTML] Safety of Oral Amphetamine Administered during Positron Emission Tomography Scans in Medically Screened Humans
LD Weidner, A Paris, WG Frankle, R Narendran - PloS one, 2015 - journals.plos.org
Changes in endogenous dopamine levels can be detected in humans using positron
emission tomography scans by measuring the amount by which a specific D 2/3 radioligand is …
emission tomography scans by measuring the amount by which a specific D 2/3 radioligand is …
The limited specificity and utility of the ABCG2 inhibitor Ko143 for PET imaging
LD Weidner, SS Zoghbi, S Lu, S Shukla… - … of Pharmacology and …, 2015 - ASPET
Imaging ATP-binding cassette (ABC) transporter activity in vivo with positron emission
tomography requires both a substrate and a transporter inhibitor. However, for ABCG2, there is no …
tomography requires both a substrate and a transporter inhibitor. However, for ABCG2, there is no …
Sensitivity of Gram stain in the diagnosis of urethritis in men
MA Orellana, ML Gómez-Lus, D Lora - Sexually transmitted infections, 2012 - sti.bmj.com
Background Acute urethritis is among the most common types of sexually transmitted diseases
in men. The diagnosis usually requires microscopic evidence of urethritis, but sometimes …
in men. The diagnosis usually requires microscopic evidence of urethritis, but sometimes …
[BOOK][B] The Role of ABC Transporters and Inflammation in Drug-Resistant Epilepsy
LD Weidner - 2017 - search.proquest.com
… of D-luciferin into the mouse brain before (top) and after administration of 10 mg/kg Ko143
(bottom). Because D-… of BCRP with Ko143 is necessary for uptake of D-luciferin into the brain. …
(bottom). Because D-… of BCRP with Ko143 is necessary for uptake of D-luciferin into the brain. …
[PDF][PDF] RaySearch Laboratories AB (publ) March 29, 2023℅ David Hedfors Quality and Regulatory Affairs Director Eugeniavagen 18 Stockholm, 113 68
R Class, II Class - 2023 - accessdata.fda.gov
… Lora D. Weidner -S Digitally signed by Lora D. …