Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a progressive
loss of dopaminergic neurons in the substantia nigra (SN). The present study was designed to …
loss of dopaminergic neurons in the substantia nigra (SN). The present study was designed to …
Hydrogen sulfide attenuates lipopolysaccharide‐induced inflammation by inhibition of p38 mitogen‐activated protein kinase in microglia
LF Hu, PTH Wong, PK Moore… - Journal of …, 2007 - Wiley Online Library
The present study attempts to investigate the effect of H 2 S on lipopolysaccharide (LPS)‐induced
inflammation in both primary cultured microglia and immortalized murine BV‐2 …
inflammation in both primary cultured microglia and immortalized murine BV‐2 …
[HTML][HTML] Application and interpretation of current autophagy inhibitors and activators
Y Yang, L Hu, H Zheng, C Mao, W Hu… - Acta Pharmacologica …, 2013 - nature.com
Autophagy is the major intracellular degradation system, by which cytoplasmic materials are
delivered to and degraded in the lysosome. As a quality control mechanism for cytoplasmic …
delivered to and degraded in the lysosome. As a quality control mechanism for cytoplasmic …
Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function
Hydrogen sulfide (H 2 S) has been proposed as a novel neuromodulator, which plays critical
roles in the central nervous system affecting both neurons and glial cells. However, its …
roles in the central nervous system affecting both neurons and glial cells. However, its …
Hydrogen sulfide in the mammalian cardiovascular system
YH Liu, M Lu, LF Hu, PTH Wong… - Antioxidants & redox …, 2012 - liebertpub.com
For more than a century, hydrogen sulfide (H 2 S) has been regarded as a toxic gas. This
review surveys the growing recognition of the role of H 2 S as an endogenous signaling …
review surveys the growing recognition of the role of H 2 S as an endogenous signaling …
Hydrogen sulfide: neurophysiology and neuropathology
LF Hu, M Lu, PT Hon Wong, JS Bian - Antioxidants & redox signaling, 2011 - liebertpub.com
Hydrogen sulfide (H 2 S) was known to be a toxic gas and an environmental hazard for many
decades. However, it is now recognized that H 2 S may serve as a gaseous mediator that …
decades. However, it is now recognized that H 2 S may serve as a gaseous mediator that …
Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake
M Lu, LF Hu, G Hu, JS Bian - Free Radical Biology and Medicine, 2008 - Elsevier
Excess extracellular glutamate, the main excitatory neurotransmitter, may result in excitotoxicity
and neural injury. The present study was designed to study the effect of hydrogen sulfide …
and neural injury. The present study was designed to study the effect of hydrogen sulfide …
Hydrogen sulfide protects MC3T3-E1 osteoblastic cells against H2O2-induced oxidative damage—implications for the treatment of osteoporosis
ZS Xu, XY Wang, DM Xiao, LF Hu, M Lu, ZY Wu… - Free Radical Biology …, 2011 - Elsevier
Osteoporosis is a bone disease that leads to an increased risk of fracture. Oxidative damage
is an important contributor to the morphological and functional changes in the development …
is an important contributor to the morphological and functional changes in the development …
Hydrogen sulphide regulates calcium homeostasis in microglial cells
Hydrogen sulphide (H 2 S), which is produced endogenously from L‐cysteine in mammalian
tissues, has been suggested to function as a neuromodulator in the brain. However, the …
tissues, has been suggested to function as a neuromodulator in the brain. However, the …
α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson's disease
…, YT Ma, YP Yang, Y Fan, ZH Qin, CF Liu, LF Hu - Aging cell, 2021 - Wiley Online Library
The cell‐to‐cell transfer of α‐synuclein (α‐Syn) greatly contributes to Parkinson's disease (PD)
pathogenesis and underlies the spread of α‐Syn pathology. During this process, …
pathogenesis and underlies the spread of α‐Syn pathology. During this process, …