Data from in vitro plasma protein binding experiments that determine the fraction of protein-bound
drug are frequently used in drug discovery to guide structure design and to prioritize …

… Li Di dedicates this book to: My parents: I am infinitely in debt to you My sisters, Ning and
Qing: for being my best friends My children, Kevin and Sophia: I am very proud of you. Ed …

The recent advances in high throughput screening for biological activities and combinatorial
chemistry have greatly expanded the number of drug candidates. Rapid screening for BBB …

With the application of Internet of Things and services to manufacturing, the fourth stage of
industrialization, referred to as Industrie 4.0, is believed to be approaching. For Industrie 4.0 to …

Five-hundred-meter Aperture Spherical radio Telescope (FAST) is a Chinese mega-science
project to build the largest single dish radio telescope in the world. Its innovative …

The worldwide outbreak of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral …

Interest in the development of sensitive, selective, rapid, and cost-effective biosensors for
biomedical analysis, environmental monitoring, and the detection of bioterrorism agents is …

Covalent organic frameworks (COFs) are a category of promising materials in the field of
solar-driven hydrogen (H 2 ) evolution, but their applications are limited by the speedy …

Background The role of endovascular therapy for acute stroke with a large infarction has not
been extensively studied in differing populations. Methods We conducted a multicenter, …

Graphene is a monolayer of tightly packed carbon atoms that possesses many interesting
properties and has numerous exciting applications. In this work, we report the antibacterial …