Anti-inflammatory activity of macrolide antibiotics

…, A Ialenti, P Maffia, L Sautebin, L Rombolà… - … of Pharmacology and …, 2000 - ASPET
The effect of four macrolide antibiotics (roxithromycin, clarithromycin, erythromycin, and
azithromycin) on the generation of some mediators and cytokines involved in the inflammatory …

[HTML][HTML] Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages

F D'Acquisto, T Iuvone, L Rombolà, L Sautebin… - FEBS letters, 1997 - Elsevier
We investigated the involvement of NF-κB in the regulation of COX-2 protein expression and
prostaglandin production in LPS-stimulated J774 macrophages. Incubation of J774 cells …

Neuropharmacology of the essential oil of bergamot

G Bagetta, LA Morrone, L Rombolà, D Amantea… - Fitoterapia, 2010 - Elsevier
Bergamot (Citrus bergamia, Risso) is a fruit most knowledgeable for its essential oil (BEO)
used in aromatherapy to minimize symptoms of stress-induced anxiety and mild mood …

Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat

C Nucci, R Tartaglione, L Rombolà, LA Morrone… - Neurotoxicology, 2005 - Elsevier
High intraocular pressure (IOP)-induced ischemia is a model for retinal neurodegeneration
that recapitulates pathological features almost identical to those seen in patients after central …

Retinal damage caused by high intraocular pressure–induced transient ischemia is prevented by coenzyme Q10 in rat

…, R Mancino, A Spano, F Cavaliere, L Rombola… - International Review of …, 2007 - Elsevier
Recent studies support a role for excitotoxicity in the development of retinal ganglion cell (RGC)
damage in subjects suffering from glaucoma. Coenzyme Q10 (CoQ10), an essential …

Role of IL-6 in the pleurisy and lung injury caused by carrageenan

…, G De Sarro, G Costantino, L Rombola… - The Journal of …, 1999 - journals.aai.org
In the present study we used IL-6 knockout mice (IL-6KO) to evaluate the role of IL-6 in the
inflammatory response caused by injection of carrageenan into the pleural space. Compared …

[HTML][HTML] Bergamot essential oil attenuates anxiety-like behaviour in rats

L Rombolà, L Tridico, D Scuteri, T Sakurada… - Molecules, 2017 - mdpi.com
Preclinical studies have recently highlighted that bergamot essential oil (BEO) is endowed
with remarkable neurobiolological effects. BEO can affect synaptic transmission, modulate …

[HTML][HTML] Pharmacokinetic interactions between herbal medicines and drugs: their mechanisms and clinical relevance

L Rombolà, D Scuteri, S Marilisa, C Watanabe… - Life, 2020 - mdpi.com
The therapeutic efficacy of a drug or its unexpected unwanted side effects may depend on
the concurrent use of a medicinal plant. In particular, constituents in the medicinal plant …

Implication of limonene and linalyl acetate in cytotoxicity induced by bergamot essential oil in human neuroblastoma cells

…, A Ciociaro, L Berliocchi, MGV Cassiano, L Rombolà… - Fitoterapia, 2013 - Elsevier
Bergamot (Citrus bergamia, Risso et Poiteau) essential oil (BEO) is a widely used plant extract
showing anxiolytic, analgesic and neuroprotective effects in rodents; also, BEO activates …

[HTML][HTML] Aromatherapy and aromatic plants for the treatment of behavioural and psychological symptoms of dementia in patients with Alzheimer's disease: clinical …

D Scuteri, LA Morrone, L Rombolà, PR Avato… - Evidence-Based …, 2017 - hindawi.com
The treatment of agitation and aggression, typical Behavioural and Psychological Symptoms
of Dementia (BPSDs) of Alzheimer’s Disease (AD), is one of the most complicated aspects …