Characterization of phencyclidine-induced effects on neuropeptide Y systems in the rat caudate-putamen

LP Midgley, LG Bush, JW Gibb, GR Hanson - Brain research, 1992 - Elsevier
Multiple administrations of the psychotominetic drug, phencyclidine-HC1 (PCP), decreased
striatal neuropeptide Y-like immunoreactivity (NPY-LI) levels in a dose-dependent manner. …

Dynamic dopaminergic regulation of neuropeptide Y systems in discrete striatal and accumbens regions

LP Midgley, JD Wagstaff, NA Singh, LG Bush… - European journal of …, 1994 - Elsevier
In this study we evaluated the effects of multiple administrations of selective dopamine D 1
and D 2 receptor agonists and antagonists on striatal, nigral, accumbens, pallidal and cortical …

N-methyl-d-aspartate receptors mediate dopamone-induced changes in extrapyramidal and limbic dynorphin systems

NA Singh, LP Midgley, LG Bush, JW Gibb, GR Hanson - Brain research, 1991 - Elsevier
The N-methyl-d-aspartate (NMDA)-type glutamate receptor was shown to mediate dopamine-induced
dynorphin A (Dyn) changes in extrapyramidal and limbic structures. MK801, a …

Differential regulation of neuropeptide Y systems in limbic structures of the rat.

LP Midgley, LG Bush, JW Gibb, GR Hanson - Journal of Pharmacology and …, 1993 - ASPET
Neuropeptide Y-like immunoreactivity (NPYLI) in the frontal cortex and nucleus accumbens
was significantly decreased after acute and multiple administrations of phencyclidine-HCl (…

[HTML][HTML] Comparison of responses by neuropeptide systems in rat to the psychotropic drugs, methamphetamine, cocaine and PCP

GR Hanson, LP Midgley, LG Bush… - Problems of Drug …, 1989 - books.google.com
Similar schizophrenia-like psychotic episodes occur following intense use of methamphetamine
(METH), cocaine and phencyclidine (PCP) and are thought to relate to the impact of …

Response of extrapyramidal and limbic neurotensin systems to phencyclidine treatment

GR Hanson, LP Midgley, LG Bush, JW Gibb - European journal of …, 1995 - Elsevier
Although phencyclidine (PCP) has several neurochemical effects, the most pharmacologically
relevant are thought to be its ability to antagonize the activity of N-methyl-d-aspartate (…

Science, science policy, and risk-based management

LP Midgley - ASTM special technical publication, 1997 - books.google.com
Recent national awareness of the economic infeasibility of remediating hazardous waste
sites to background levels has sparked increased interest in the role of science policy in the …

[PDF][PDF] An isothermal experimental study of the unsteady fluid mechanics of gas turbine fuel injector flowfields

K Midgley - 2005 - repository.lboro.ac.uk
Low-emissions combustor design is crucially important to gas turbine engine manufacturers.
Unfortunately, many designs are susceptible to unsteady oscillations that can result in …

A history of chemically and radiatively important gases in air deduced from ALE/GAGE/AGAGE

…, LP Steele, G Sturrock, PM Midgley… - Journal of …, 2000 - Wiley Online Library
We describe in detail the instrumentation and calibrations used in the Atmospheric Lifetime
Experiment (ALE), the Global Atmospheric Gases Experiment (GAGE), and the Advanced …

[PDF][PDF] Regulation of neuropeptide Y-containing neurons in the basal ganglia and limbic system of the rat

LP Midgley - 1993 - core.ac.uk
… 4 have been reprinted from the following manuscripts: Midgley et aI., Differential regulation of
… and Midgley et aI., Dynamic dopaminergic regulation of neuropeptide Y systems in discrete …