In a study of Lassa fever in Sierra Leone, West Africa, we identified two variables associated
with a high risk of death, and we evaluated the efficacy of ribavirin and Lassa virus–…

We measured levels of virus in sequential specimens from 137 patients with Lassa fever. The
probability of fatal disease increased significantly with the level of viremia measured either …

The virion proteins of two strains of Ebola virus were compared by SDS-polyacrylamide gel
electrophoresis (PAGE) and radioimmunoprecipitation (RIP). Seven virion proteins were …

Postmortem examination of 21 virologically documented cases of Lassa fever, including 6
complete autopsies, was performed as part of a field study of community-acquired Lassa fever …

… However, the same treatment of Marburg and Ebola viruses left residual infectivity, and
longer treatment diminished antigenicity (LH Elliott andK. M. Johnson, unpublished data). …

A previously unrecognized disease, hantavirus pulmonary syndrome, was described following
an outbreak of severe, often lethal, pulmonary illness in the southwestern United States in …

A hypothetical mode ofinhibition of protein kinase C (PKC) by the natural product
staurosporine has been used as a basis for thedesign of substituted bisindolylmaleimides with …

Numerous rodents were trapped for serologic and virologic studies following the identification
of a hantavirus pulmonary syndrome (HPS) case in Dade County, Florida. Cotton rats (…

In order to explore the significance of a previous observation that the most important pathologic
changes in fatal Lassa fever are hepatic, we have studied postmortem liver biopsies from …

It has been well established that patients with malignant glioblastomas exhibit T cell anergy.
In this report, we further investigate the nature of this T cell anergy. The results demonstrate …