A series of N-hydroxyurea derivatives have been prepared and examined as inhibitors of 5-lipoxygenase.
Oral activity was established by examining the inhibition of LTB 4 biosynthesis …

Metabolism of tert-butyl hydroperoxide (TBHP, 2.0 mm) by glutathione peroxidase within
isolated rat hepatocytes caused a rapid oxidation of intracellular reduced glutathione and …

The purpose of this investigation was to correlate the in vitro and in vivo toxicity of the
hepatotoxicant, acetaminophen. Hamsters were pretreated with either phenobarbital (70 mg/kg) or …

The bronchopulmonary pharmacology of SK&F 104353 [2(S)-hydroxy-3(R)-[2(2-carboxyethyl)thio]-3[2-(8-
phenyloctyl)phenyl]-propanoic acid], a potent and selective leukotriene (LT) …

Oxmetidine is a potent and specific antagonist of the histamine H2-receptor. Oxmetidine is
also cytotoxic to isolated rat hepatocytes through inhibition of mitochondrial oxidative …

… of LA, one of which has not been reported previously as a metabolite of LA in mammalian
microsomal incubations. These products, 12-(w)-hydroxy-LA, 1 1-(w-1)-hydroxy-LA, and a …

A sediment budget is constructed for the Lower Mississippi River prior to the introduction of
most human modifications. Components of the budget are derived from historical data …

'Xx *•- mm awthe original ala of this work was to invastlgate conditions of gypsum precipitation
which would yield a good filtering, clustered crystal a® obtained In mt process phosphoric …

… Mississippi et de la Rivière Rouge. Les aménagements successifs dans ce secteur illustrent
la puissance des effets de la manipulation du cours d’eau sur son delta. De la création du « …

… "Rule 66" was a benchmark Los Angeles law which separated organic solvents into two
categories, depending on whether they contributed to the formation of smog. This rule is now …