B. Regional distribution of pre-and postganglionic neurons C. Ultrastructure of the neuroeffector
junction III. Neuronal mechanisms A. Resting release of acetylcholine B. Release of …

Publisher Summary The plasma level of free choline is remarkably constant at about 10 pM
in animals and human. Ingestion of food, especially when rich in choline or lecithin, …

In the central nervous system, choline is an essential precursor of choline-containing
phospholipids in neurons and glial cells and of acetylcholine in cholinergic neurons. In order to …

A marked increase of choline release from rat hippocampal slices was observed when the
slices were superfused with oxygen-free buffer, indicating hypoxia-induced hydrolysis of …

1 11. It is now evident that receptor activation and Ca+ mobilization are coupled by a G-protein
and an enzyme (PI-PLC) t that catalyzes the hydrolysis of PIP, to the Ca*+-mobilizing …

The present study is concerned with the uptake and metabolism of choline by the rat brain.
Intraperitoneal administration of choline chloride (4‐60 mg/kg) caused a dose‐dependent …

Using the microdialysis technique and sensitive HPLC procedures for the determination of
acetylcholine (ACh) and ethanol, we investigated the release of ACh in rat hippocampus after …

The concentrations of free choline in blood plasma from a peripheral artery and from the
transverse sinus, in the CSF, and in total brain homogenate, have been measured in untreated …

Central cholinergic neurotransmission was studied in learning‐impaired transgenic mice
expressing human acetylcholinesterase (hAChE‐Tg). Total catalytic activity of AChE was …

The influence of choline availability on acetylcholine (ACh) release in the hippocampus of
the awake rat was investigated using the microdialysis procedure. Three treatments …