Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

MR Montminy, KA Sevarino… - Proceedings of the …, 1986 - National Acad Sciences
We have examined the regulation of somatostatin gene expression by cAMP in PC12 rat
pheochromocytoma cells transfected with the rat somatostatin gene. Forskolin at 10 microM …

Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits

…, M Talantova, Y Shin, J Cui, S Tu, KA Sevarino… - Nature, 2002 - nature.com
The N-methyl-d-aspartate subtype of glutamate receptor (NMDAR) serves critical functions
in physiological and pathological processes in the central nervous system, including …

A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function

RZ Terwilliger, D Beitner-Johnson, KA Sevarino… - Brain research, 1991 - Elsevier
Previous studies have shown that chronic morphine increases levels of the G-protein
subunits G iα and G oα , adenylate cyclase, cyclic AMP-dependent protein kinase, and certain …

Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

…, G Pecht, S Heinemann, KA Sevarino - Journal of …, 1995 - Soc Neuroscience
Ionotropic glutamate receptors are composed of homomeric or heteromeric configurations
of glutamate receptor subunits. We have cloned a member of a novel class of the rat …

The biology of pro-thyrotropin-releasing hormone-derived peptides

EA Nillni, KA Sevarino - Endocrine reviews, 1999 - academic.oup.com
A. Biosynthesis and processing of pro-TRH B. Intracellular sites of pro-TRH processing C.
Tissue-specific processing of pro-TRH D. The role of PCs and CPs E. Neuropeptide and …

The thyrotropin-releasing hormone (TRH) hypothesis of homeostatic regulation: implications for TRH-based therapeutics

KA Gary, KA Sevarino, GG Yarbrough, AJ Prange… - … of Pharmacology and …, 2003 - ASPET
The functions of thyrotropin-releasing hormone (TRH) in the central nervous system (CNS)
can be conceptualized as performed by four anatomically distinct components that together …

Chronic Cocaine Treatment Decreases Levels of the G Protein Subunits G and G in Discrete Regions of Rat Brain

…, RZ Terwilliger, JR Walker, KA Sevarino… - Journal of …, 1990 - Wiley Online Library
A possible role for G proteins in contributing to the chronic actions of cocaine was investigated
in three rat brain regions known to exhibit electrophysiological responses to chronic …

Concurrent alcohol and tobacco treatment: Effect on daily process measures of alcohol relapse risk.

NL Cooney, MD Litt, KA Sevarino, L Levy… - Journal of Consulting …, 2015 - psycnet.apa.org
Objective: The aim of this study was to compare the effects of alcohol treatment along with
concurrent smoking treatment or delayed smoking treatment on process measures related to …

Comparison of intravenous cocaethylene and cocaine in humans

CL Hart, P Jatlow, KA Sevarino, EF McCance-Katz - Psychopharmacology, 2000 - Springer
Rationale: Cocaethylene is a pharmacologically active homolog and metabolite of cocaine,
formed by transesterification of cocaine in the presence of ethanol. Here we relate findings …

[8] Cytochrome-c oxidase from Saccharomyces cerevisiae

RO Poyton, B Goehring, M Droste, KA Sevarino… - Methods in …, 1995 - Elsevier
Publisher Summary This chapter discusses the methods for the isolation and characterization
of the nine-subunit yeast holo-cytochrome-c oxidase and its subunits as well as …