Effects of monoterpenes on ion channels of excitable cells

M Oz, Y Lozon, A Sultan, KHS Yang… - Pharmacology & …, 2015 - Elsevier
Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of
plant-derived ‘essential oils’. Monoterpenes such as menthol, carvacrol, and eugenol have …

Effects of cannabidiol on the function of α7-nicotinic acetylcholine receptors

M Mahgoub, SY Keun-Hang, V Sydorenko… - European journal of …, 2013 - Elsevier
The effects of cannabidiol (CBD), a non-psychoactive ingredient of cannabis plant, on the
function of the cloned α 7 subunit of the human nicotinic acetylcholine (α 7 nACh) receptor …

[HTML][HTML] Menthol binding and inhibition of α7-nicotinic acetylcholine receptors

A Ashoor, JC Nordman, D Veltri, KHS Yang, L Al Kury… - PloS one, 2013 - journals.plos.org
Menthol is a common compound in pharmaceutical and commercial products and a popular
additive to cigarettes. The molecular targets of menthol remain poorly defined. In this study …

Menthol inhibits 5-HT3 receptor–mediated currents

A Ashoor, JC Nordman, D Veltri, KHS Yang… - … of Pharmacology and …, 2013 - ASPET
The effects of alcohol monoterpene menthol, a major active ingredient of the peppermint
plant, were tested on the function of human 5-hydroxytryptamine type 3 (5-HT 3 ) receptors …

Effects of the endogenous cannabinoid anandamide on voltage‐dependent sodium and calcium channels in rat ventricular myocytes

LT Al Kury, OI Voitychuk, KHS Yang… - British journal of …, 2014 - Wiley Online Library
Background and Purpose The endocannabinoid anandamide ( N ‐arachidonoyl ethanolamide;
AEA ) exerts negative inotropic and antiarrhythmic effects in ventricular myocytes. …

Effects of cannabidiol on contractions and calcium signaling in rat ventricular myocytes

RM Ali, LT Al Kury, KHS Yang, A Qureshi, M Rajesh… - Cell Calcium, 2015 - Elsevier
Cannabidiol (CBD), a major nonpsychotropic cannabinoid found in Cannabis plant, has been
shown to influence cardiovascular functions under various physiological and pathological …

[HTML][HTML] α7 nicotinic acetylcholine receptor interaction with G proteins in breast cancer cell proliferation, motility, and calcium signaling

M Oz, JR King, KHS Yang, S Khushaish… - PLoS …, 2023 - journals.plos.org
Chronic smoking is a primary risk factor for breast cancer due to the presence of various toxins
and carcinogens within tobacco products. Nicotine is the primary addictive component of …

Inhibition of human α7 nicotinic acetylcholine receptors by cyclic monoterpene carveol

…, SJ Lansdell, T Prytkova, B Sadek, KHS Yang… - European Journal of …, 2016 - Elsevier
Cyclic monoterpenes are a group of phytochemicals with antinociceptive, local anesthetic,
and anti-inflammatory actions. Effects of cyclic monoterpenes including vanilin, pulegone, …

Curcumin acts as a positive allosteric modulator of α7-nicotinic acetylcholine receptors and reverses nociception in mouse models of inflammatory pain

…, H Al Samri, A Brodzik, Y Alkhlaif, KHS Yang… - … of Pharmacology and …, 2018 - ASPET
Effects of curcumin, a major ingredient of turmeric, were tested on the function of the α 7 -subunit
of the human nicotinic acetylcholine (α 7 -nACh) receptor expressed in Xenopus …

Cellular approaches to the interaction between cannabinoid receptor ligands and nicotinic acetylcholine receptors

M Oz, L Al Kury, SY Keun-Hang, M Mahgoub… - European journal of …, 2014 - Elsevier
Cannabinoids are among the earliest known drugs to humanity. Cannabis plant contains
various phytochemicals that bind to cannabinoid receptors. In addition, synthetic and …