[HTML][HTML] Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection
Although myocarditis and pericarditis were not observed as adverse events in coronavirus
disease 2019 (COVID-19) vaccine trials, there have been numerous reports of suspected …
disease 2019 (COVID-19) vaccine trials, there have been numerous reports of suspected …
Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD (P) H oxidase and endothelial nitric oxide synthase
…, J Sadowski, C Ratnatunga, R Pillai, KM Channon - Circulation, 2002 - Am Heart Assoc
Background— Increased superoxide production contributes to reduced vascular nitric oxide
(NO) bioactivity and endothelial dysfunction in experimental models of diabetes. We …
(NO) bioactivity and endothelial dysfunction in experimental models of diabetes. We …
[HTML][HTML] Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge
…, M Jenkinson, C Antoniades, KM Channon… - …, 2021 - thelancet.com
Background The medium-term effects of Coronavirus disease (COVID-19) on organ health,
exercise capacity, cognition, quality of life and mental health are poorly understood. Methods …
exercise capacity, cognition, quality of life and mental health are poorly understood. Methods …
Vascular superoxide production by NAD (P) H oxidase: association with endothelial dysfunction and clinical risk factors
…, C Ratnatunga, R Pillai, KM Channon - Circulation …, 2000 - Am Heart Assoc
Superoxide anion plays important roles in vascular disease states. Increased superoxide
production contributes to reduced nitric oxide (NO) bioactivity and endothelial dysfunction in …
production contributes to reduced nitric oxide (NO) bioactivity and endothelial dysfunction in …
Detecting human coronary inflammation by imaging perivascular fat
…, S Achenbach, S Neubauer, KM Channon… - Science translational …, 2017 - science.org
Early detection of vascular inflammation would allow deployment of targeted strategies for
the prevention or treatment of multiple disease states. Because vascular inflammation is not …
the prevention or treatment of multiple disease states. Because vascular inflammation is not …
[HTML][HTML] Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc …
…, J Deanfield, S Neubauer, JC Hopewell, KM Channon… - The Lancet, 2018 - thelancet.com
Background Coronary artery inflammation inhibits adipogenesis in adjacent perivascular fat.
A novel imaging biomarker—the perivascular fat attenuation index (FAI)—captures …
A novel imaging biomarker—the perivascular fat attenuation index (FAI)—captures …
Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease
NJ Alp, KM Channon - Arteriosclerosis, thrombosis, and vascular …, 2004 - Am Heart Assoc
Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), is a key signaling
molecule in vascular homeostasis. Loss of NO bioavailability due to reduced synthesis and …
molecule in vascular homeostasis. Loss of NO bioavailability due to reduced synthesis and …
A myocardial Nox2 containing NAD (P) H oxidase contributes to oxidative stress in human atrial fibrillation
…, C Ratnatunga, R Pillai, KM Channon… - Circulation …, 2005 - Am Heart Assoc
Human atrial fibrillation (AF) has been associated with increased atrial oxidative stress. In
animal models, inhibition of reactive oxygen species prevents atrial remodeling induced by …
animal models, inhibition of reactive oxygen species prevents atrial remodeling induced by …
5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin …
…, C Ratnatunga, R Pillai, H Refsum, KM Channon - Circulation, 2006 - Am Heart Assoc
Background— The circulating form of folic acid, 5-methyltetrahydrofolate (5-MTHF), may
have beneficial effects on endothelial function; however, its mechanisms of action remain …
have beneficial effects on endothelial function; however, its mechanisms of action remain …
Risk of myocarditis after sequential doses of COVID-19 vaccine and SARS-CoV-2 infection by age and sex
Background: Myocarditis is more common after severe acute respiratory syndrome coronavirus
2 infection than after COVID-19 vaccination, but the risks in younger people and after …
2 infection than after COVID-19 vaccination, but the risks in younger people and after …