User profiles for Juan-José Canales

Juan J. Canales

Professor, Head of School, Victoria University of Wellington, New Zealand
Verified email at vuw.ac.nz
Cited by 4492

Molecular mechanism of acute ammonia toxicity: role of NMDA receptors

P Monfort, E Kosenko, S Erceg, JJ Canales… - Neurochemistry …, 2002 - Elsevier
Acute administration of large doses of ammonia leads to the rapid death of animals. This
article reviews the role of excessive activation of N-methyl-d-aspartate (NMDA) receptors in the …

The high affinity dopamine uptake inhibitor, JHW 007, blocks cocaine-induced reward, locomotor stimulation and sensitization

…, A Ferragud, J Murga, M Cardá, JJ Canales - European …, 2010 - Elsevier
The discovery and evaluation of high affinity dopamine transport inhibitors with low abuse
liability is an important step toward the development of efficacious medications for cocaine …

Chronic hyperammonemia alters motor and neurochemical responses to activation of group I metabotropic glutamate receptors in the nucleus accumbens in rats in …

JJ Canales, A Elayadi, M Errami, M Llansola… - Neurobiology of …, 2003 - Elsevier
Hyperammonemia leads to altered cerebral function and neurological alterations in patients
with hepatic encephalopathy. We studied the effects of hyperammonemia in rats on the …

Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants

C Montoliu, M Humet, JJ Canales, J Burda… - … of Pharmacology and …, 2002 - ASPET
Excitotoxicity has been implicated in the etiology of ischemic stroke and chronic
neurodegenerative disorders. Hence, the development of novel neuroprotectant molecules that …

[HTML][HTML] Exposure to N-ethyl-N-nitrosourea in adult mice alters structural and functional integrity of neurogenic sites

…, A Ferragud, L Bonet-Ponce, JJ Canales… - PLoS …, 2012 - journals.plos.org
Background Previous studies have shown that prenatal exposure to the mutagen N-ethyl-N-nitrosourea
(ENU), a N-nitroso compound (NOC) found in the environment, disrupts …

The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens

…, JM García-Verdugo, JJ Canales - 2013 - repositori.uji.es
Benztropine (BZT) analogs, a family of agents with high affinity for the dopamine transporter
have been postulated as potential treatments in stimulant abuse due to their ability to …

Las políticas públicas: actualidad y perspectivas

JM Canales Aliende - 2015 - rua.ua.es
… José Manuel Canales Aliende en “Las políticas públicas: actualidad y perspectivas”,
reflexiona sobre su naturaleza y actores, identifica procesos y resalta la importancia de una …

Reconocimiento Geofísico de estructuras submarinas situadasal Norte y Sur del Archipiélago Canario

JJD Canales - Revista de la Sociedad Geológica de España, 1988 - dialnet.unirioja.es
En 1981 se realizó una campaña de geofísica marina en aguas del Archipiélago Canario,
para definir las estructuras submarinas de esta parte del Atlántico Norte, registrándose datos …

[PDF][PDF] Estudio mediante sÌsmica de reflexión de un grupo de estructuras submarinas situadas al Norte y Sur del archipelago Canario

JJD Canales, BJ Collette - Acta geológica hispánica, 1989 - raco.cat
El Archipitlago Canario es un complejo volcinico intraplaca situado al oeste del margen
occidental africano. La realizaci6n de una cam~ afia de sísmica de reflexi6n ha~ ermitido …

Results from the ESCI-N3. 1 and ESCI-N3. 2 marine deep seismic profiles in the northwestern Galicia Margin

…, AP Estaún, JJD Canales… - Revista de la …, 1995 - produccioncientifica.usal.es
El perfil marino ESCI-N3 registra 20 s de datos de sísmica de reflexión vertical en el noroeste
de Galicia. En este trabajo se analizan dos segmentos del perfil, que incluyen la llanura …