4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl) ethyl] 5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride …

…, C Marcy, PE Rouby, J Simiand, J Guitard… - … of Pharmacology and …, 2002 - ASPET
… Danielle Gully, Michel Geslin, Laurence Serva, Evelyne Fontaine, Pierre Roger, Christine
Lair, Valerie Darre, Claudine Marcy, Pierre-Eric Rouby, Jacques Simiand, Josette Guitard, …

Antidepressant profile in rodents of SR 58611A, a new selective agonist for atypical β-adrenoceptors

J Simiand, PE Keane, J Guitard, X Langlois… - European journal of …, 1992 - Elsevier
β 2 -Adrenoceptor agonists possess antidepressant-like activity in animals and man, but
their peripheral side-effects prevent their therapeutic use. Atypical β-adrenoceptors have not …

Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks

P Venault, G Chapouthier, LP de Carvalho, J Simiand… - Nature, 1986 - nature.com
Benzodiazepines are widely used anxiolytics and anticonvulsants, and their potent sedative
properties are routinely used in presurgical anaesthesia. However, they are also known to …

The staircase test in mice: a simple and efficient procedure for primary screening of anxiolytic agents

J Simiand, PE Keane, M Morre - Psychopharmacology, 1984 - Springer
… The authors would like to thank MarieChristine Barnouin and Josette Guitard for their excellent
technical assistance and Marie Roussel for preparation of the manuscript. Diazepam and …

[CITATION][C] … CHRISTINE LAIR, VALERIE DARRE, CLAUDINE MARCY, PIERRE-ERIC ROUBY, JACQUES SIMIAND, JOSETTE GUITARD, GEORGETTE GOUT, REGIS …

R PRUSS, B SCATTON, JP MAFFRAND, G LE FUR - THE JOURNAL OF …, 2002

Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents

G Griebel, J Stemmelin, B Scatton - Biological psychiatry, 2005 - Elsevier
BACKGROUND: The endocannabinoid system has been implicated in the modulation of
emotional processes. METHODS: These experiments aimed to investigate the effects of the …

Enhancement of performance by methyl β-carboline-3-carboxylate, in learning and memory tasks

P Venault, G Chapouthier, J Simiand, RH Dodd… - Brain research …, 1987 - Elsevier
Benzodiazepines are known to induce a profound anterograde amnesia in man. In this
report, it is shown that methyl β-carboline-3-carboxylate (β-CCM), an inverse agonist of the …

[PDF][PDF] Tetrazepam: a benzodiazepine which dissociates sedation from other benzodiazepine activities. I. Psychopharmacological profile in rodents.

PE Keane, J Simiand, M Morre, K Biziere - Journal of Pharmacology and …, 1988 - Citeseer
Materialsand Methods Animals. Swiss albino CD, male mice, weighing 19 to 24 g, and male
CD rats weighing 160 to 200 g (except for the conflict test in which weights were 300 to 450 …

SR146131: A new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II: In vivo pharmacological characterization

E Bignon, R Alonso, M Arnone, R Boigegrain… - … of Pharmacology and …, 1999 - ASPET
SR146131 is a potent and selective agonist at cholecystokinin subtype 1 (CCK 1 ) receptors
in vitro. The present study evaluates the activity of the compound in vivo. SR146131 …

Comédie des Champs-Elysées: Marcel Achard: Pétrus

EH Guitard - Revue d'Histoire de la Pharmacie, 1934 - persee.fr
… sem-link sem-link Eugène-Humbert GuitardGuitard Eugène-Humbert. Comédie des
Champs-Elysées : Marcel Achard : Pétrus. In: Revue d'histoire de la pharmacie, supplément …