Molecular chaperone functions of heat-shock proteins
JP Hendrick, FU Hartl - Annual review of biochemistry, 1993 - annualreviews.org
Molecular chaperones, many of them so-called heat-shock or stress proteins (hsps), have
emerged over recent years as an important topic in cell biology. The functions of these …
emerged over recent years as an important topic in cell biology. The functions of these …
The binding cascade of SecB to SecA to SecYE mediates preprotein targeting to the E. coli plasma membrane
FU Hartl, S Lecker, E Schiebel, JP Hendrick, W Wickner - Cell, 1990 - cell.com
The export of many E. coli proteins such as pmOmpA requires the cytosolic chaperone SecB
and the membrane-bound preprotein translocase. Translocase is a multisubunit enzyme …
and the membrane-bound preprotein translocase. Translocase is a multisubunit enzyme …
The purified E. coli integral membrane protein SecYE is sufficient for reconstitution of SecA-dependent precursor protein translocation
L Brundage, JP Hendrick, E Schiebel, AJM Driessen… - Cell, 1990 - cell.com
We have previously reconstituted the soluble phase of precursor protein translocation in
vitro using purified proteins (the precursor proOmpA, the chaperone SecB, and the ATPase …
vitro using purified proteins (the precursor proOmpA, the chaperone SecB, and the ATPase …
Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected …
JP Hendrick, SL Wolin, J Rinke… - Molecular and cellular …, 1981 - Taylor & Francis
Small ribonucleic acid (RNA)-protein complexes precipitated by anti-Ro and anti-La antibodies
from lupus patients have been examined with emphasis on their RNA components. In …
from lupus patients have been examined with emphasis on their RNA components. In …
[HTML][HTML] In vivo observation of polypeptide flux through the bacterial chaperonin system
The quantitative contribution of chaperonin GroEL to protein folding in E. coli was analyzed.
A diverse set of newly synthesized polypeptides, predominantly between 10–55 kDa, …
A diverse set of newly synthesized polypeptides, predominantly between 10–55 kDa, …
The role of molecular chaperones in protein folding
JP Hendrick, FU Hartl - The FASEB journal, 1995 - Wiley Online Library
Folding of newly synthesized polypep tides in the crowded cellular environment requires the
assistance of so‐called molecular chaperone proteins. Chaperones of the Hsp70 class and …
assistance of so‐called molecular chaperone proteins. Chaperones of the Hsp70 class and …
[HTML][HTML] Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission
…, P Li, Q Zhang, V Krishnan, JP Hendrick… - …, 2015 - Springer
Rationale Schizophrenia remains among the most prevalent neuropsychiatric disorders, and
current treatment options are accompanied by unwanted side effects. New treatments that …
current treatment options are accompanied by unwanted side effects. New treatments that …
A 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells.
JA Steitz, C Berg, JP Hendrick… - The Journal of cell …, 1988 - rupress.org
A novel 5S RNA-protein (RNP) complex in human and mouse cells has been analyzed
using patient autoantibodies. The RNP is small (approximately 7S) and contains most of the …
using patient autoantibodies. The RNP is small (approximately 7S) and contains most of the …
Dynamics of β-amyloid reductions in brain, cerebrospinal fluid, and plasma of β-amyloid precursor protein transgenic mice treated with a γ-secretase inhibitor
…, CT Polson, J Wang, SB Roberts, JP Hendrick… - … of Pharmacology and …, 2005 - ASPET
γ-Secretase inhibitors are one promising approach to the development of a therapeutic for
Alzheimer's disease (AD). γ-Secretase inhibitors reduce brain β-amyloid peptide (Aβ), which …
Alzheimer's disease (AD). γ-Secretase inhibitors reduce brain β-amyloid peptide (Aβ), which …
Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid …
JP Hendrick, PE Hodges… - Proceedings of the …, 1989 - National Acad Sciences
We have compiled sequences of precursor proteins for 50 mitochondrial proteins for which
the mature amino terminus has been determined by amino acid sequence analysis. Included …
the mature amino terminus has been determined by amino acid sequence analysis. Included …