TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
B Liu, L Fan, S Balakrishna, A Sui, JB Morris, SE Jordt - Pain®, 2013 - Elsevier
Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations
for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful …
for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful …
[HTML][HTML] Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants
Menthol, the cooling agent in peppermint, is added to almost all commercially available
cigarettes. Menthol stimulates olfactory sensations, and interacts with transient receptor potential …
cigarettes. Menthol stimulates olfactory sensations, and interacts with transient receptor potential …
The tablet formulation of lopinavir/ritonavir provides similar bioavailability to the soft-gelatin capsule formulation with less pharmacokinetic variability and diminished …
…, T Doan, J Breitenbach, JB Morris… - JAIDS Journal of …, 2007 - journals.lww.com
Lopinavir, an HIV protease inhibitor, is coformulated with ritonavir to enhance the bioavailability
and pharmacokinetics of lopinavir. The original solid oral formulation of lopinavir/ritonavir…
and pharmacokinetics of lopinavir. The original solid oral formulation of lopinavir/ritonavir…
Transient receptor potential cation channel subfamily M member 8 channels mediate the anti‐inflammatory effects of eucalyptol
Background and Purpose Eucalyptol (1,8‐cineol), the major ingredient in the essential oil of
eucalyptus leaves and other medicinal plants, has long been known for its anti‐inflammatory …
eucalyptus leaves and other medicinal plants, has long been known for its anti‐inflammatory …
Advances in inhalation dosimetry models and methods for occupational risk assessment and exposure limit derivation
ED Kuempel, LM Sweeney, JB Morris… - … of occupational and …, 2015 - Taylor & Francis
The purpose of this article is to provide an overview and practical guide to occupational health
professionals concerning the derivation and use of dose estimates in risk assessment for …
professionals concerning the derivation and use of dose estimates in risk assessment for …
The role of toxicological science in meeting the challenges and opportunities of hydraulic fracturing
…, AE Gates, ME Honeycutt, JB Morris… - Toxicological …, 2014 - academic.oup.com
We briefly describe how toxicology can inform the discussion and debate of the merits of
hydraulic fracturing by providing information on the potential toxicity of the chemical and …
hydraulic fracturing by providing information on the potential toxicity of the chemical and …
[HTML][HTML] Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice
Addition of menthol to cigarettes may be associated with increased initiation of smoking. The
potential mechanisms underlying this association are not known. Menthol, likely due to its …
potential mechanisms underlying this association are not known. Menthol, likely due to its …
Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper …
…, KT Morgan, RP Subramaniam, JB Morris… - Toxicology and applied …, 1998 - Elsevier
This study provides a scientific basis for interspecies extrapolation of nasal olfactory irritants
from rodents to humans. By using a series of short-termin vivostudies,in vitrostudies with …
from rodents to humans. By using a series of short-termin vivostudies,in vitrostudies with …
Inhalation dosimetry of diacetyl and butyric acid, two components of butter flavoring vapors
JB Morris, AF Hubbs - Toxicological Sciences, 2009 - academic.oup.com
Occupational exposure to butter flavoring vapors (BFV) is associated with significant pulmonary
injury. The goal of the current study was to characterize inhalation dosimetric patterns of …
injury. The goal of the current study was to characterize inhalation dosimetric patterns of …
Accumulation of manganese in rat brain following intranasal administration
G Gianutsos, GR Morrow, JB Morris - Fundamental and Applied Toxicology, 1997 - Elsevier
Manganese chloride (50–800 μg) was injected unilaterally into the right nostril of rats and its
accumulation in the central nervous system (CNS) was monitored. Brain manganese levels …
accumulation in the central nervous system (CNS) was monitored. Brain manganese levels …