TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain

B Liu, L Fan, S Balakrishna, A Sui, JB Morris, SE Jordt - Pain®, 2013 - Elsevier
Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations
for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful …

[HTML][HTML] Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants

DN Willis, B Liu, MA Ha, SE Jordt, JB Morris - The FASEB Journal, 2011 - ncbi.nlm.nih.gov
Menthol, the cooling agent in peppermint, is added to almost all commercially available
cigarettes. Menthol stimulates olfactory sensations, and interacts with transient receptor potential …

The tablet formulation of lopinavir/ritonavir provides similar bioavailability to the soft-gelatin capsule formulation with less pharmacokinetic variability and diminished …

…, T Doan, J Breitenbach, JB Morris… - JAIDS Journal of …, 2007 - journals.lww.com
Lopinavir, an HIV protease inhibitor, is coformulated with ritonavir to enhance the bioavailability
and pharmacokinetics of lopinavir. The original solid oral formulation of lopinavir/ritonavir…

Transient receptor potential cation channel subfamily M member 8 channels mediate the anti‐inflammatory effects of eucalyptol

…, B Liu, SV Jabba, S Achanta, JB Morris… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose Eucalyptol (1,8‐cineol), the major ingredient in the essential oil of
eucalyptus leaves and other medicinal plants, has long been known for its anti‐inflammatory …

Advances in inhalation dosimetry models and methods for occupational risk assessment and exposure limit derivation

ED Kuempel, LM Sweeney, JB Morris… - … of occupational and …, 2015 - Taylor & Francis
The purpose of this article is to provide an overview and practical guide to occupational health
professionals concerning the derivation and use of dose estimates in risk assessment for …

The role of toxicological science in meeting the challenges and opportunities of hydraulic fracturing

…, AE Gates, ME Honeycutt, JB Morris… - Toxicological …, 2014 - academic.oup.com
We briefly describe how toxicology can inform the discussion and debate of the merits of
hydraulic fracturing by providing information on the potential toxicity of the chemical and …

[HTML][HTML] Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice

…, L Fan, YS Liu, AI Caceres, SE Jordt, JB Morris - PloS one, 2015 - journals.plos.org
Addition of menthol to cigarettes may be associated with increased initiation of smoking. The
potential mechanisms underlying this association are not known. Menthol, likely due to its …

Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper …

…, KT Morgan, RP Subramaniam, JB Morris… - Toxicology and applied …, 1998 - Elsevier
This study provides a scientific basis for interspecies extrapolation of nasal olfactory irritants
from rodents to humans. By using a series of short-termin vivostudies,in vitrostudies with …

Inhalation dosimetry of diacetyl and butyric acid, two components of butter flavoring vapors

JB Morris, AF Hubbs - Toxicological Sciences, 2009 - academic.oup.com
Occupational exposure to butter flavoring vapors (BFV) is associated with significant pulmonary
injury. The goal of the current study was to characterize inhalation dosimetric patterns of …

Accumulation of manganese in rat brain following intranasal administration

G Gianutsos, GR Morrow, JB Morris - Fundamental and Applied Toxicology, 1997 - Elsevier
Manganese chloride (50–800 μg) was injected unilaterally into the right nostril of rats and its
accumulation in the central nervous system (CNS) was monitored. Brain manganese levels …