… The rats used in this study were the same as those described by Wrathall et al. (13), males
or females of the Sprague-Dawley strain that had been subjected to spinal cord contusion …

Morphometric analyses were carried out on rat spinal cords which were injured by a weight
drop technique. A 10-g weight was dropped 0.0, 2.5, 5.0, 7.5, 10.0, or 17.5 cm onto the dura …

A weight drop technique was used to produce a contusive injury of the spinal cord in the rat.
A restricted laminectomy was carried out at T8 and the spinal column stabilized by clamps …

We have previously characterized a graded, spinal cord contusive injury in the rat. We have
now used this reproducible model to examine vascular permeability to horseradish …

The development of both histopathological changes and functional deficits was quantitatively
assessed after mild, moderate, and severe spinal cord contusive injuries. The cross-…

After spinal cord injury (SCI), about 50% of the oligodendrocytes and astrocytes in the residual
white matter at the injury site are lost by 24 h. However, chronically after SCI, the density …

Although regeneration of injured neurons does not occur after trauma in the central nervous
system (CNS), there is often significant recovery of functional capacity with time. Little is …

Interleukin-1 beta (IL-1β) is a major mediator of inflammation and a growth promoter for many
cell types that could play an important role in the consequences of traumatic spinal cord …

Excitatory amino acid (EAA) receptors play a significant role in delayed neuronal death after
ischemic and traumatic injury to the CNS. Recent data based on focal microinjection …

Acute focal injection of basic fibroblast growth factor (FGF2) protects ventral horn (VH)
neurons from death after experimental contusive spinal cord injury (SCI) at T8. Because these …