[PDF][PDF] Multiparameter analysis of human bone marrow stromal cells identifies distinct immunomodulatory and differentiation-competent subtypes

…, J Fox, F Afsari, J Lee, S Clough, C Knight, J Ashmore… - Stem cell reports, 2015 - cell.com
Bone marrow stromal cells (BMSCs, also called bone-marrow-derived mesenchymal stromal
cells) provide hematopoietic support and immunoregulation and contain a stem cell fraction …

Effects of Adrenergic and Cholinergic Agents Upon Insulin Secretion in Vitro

…, PH WRIGHT, J ASHMORE - …, 1967 - academic.oup.com
Adrenergic drugs (epinephrine, norepinephrine and isoproterenol) inhibit insulin secretion
from pieces of rat pancreas incubated with glucose (150 mg/100 ml). This inhibitory effect …

The role of hepatic glucose-6-phosphatase in the regulation of carbohydrate metabolism

J Ashmore, G Weber - Vitamins & Hormones, 1959 - Elsevier
Publisher Summary Many attempts have been made to assign to enzymes the role of
biochemical regulators as well as the function of catalysts. For example, changes in the rate of …

Blood glucose and the liver

GF Cahill Jr, J Ashmore, AE Renold… - The American Journal of …, 1959 - Elsevier
A graphical summary of those aspects of carbohydrate metabolism herein discussed, which
contribute to the regulation of blood glucose under normal and pathological conditions, is …

[PDF][PDF] Regional identity of human neural stem cells determines oncogenic responses to histone H3. 3 mutants

…, MA Marques-Torrejon, GM Morrison, J Ashmore… - Cell Stem Cell, 2021 - cell.com
Point mutations within the histone H3.3 are frequent in aggressive childhood brain tumors
known as pediatric high-grade gliomas (pHGGs). Intriguingly, distinct mutations arise in …

Glucose penetration into liver

GF Cahill JR, J Ashmore, AS Earle… - American Journal of …, 1958 - journals.physiology.org
To further define the action of insulin on liver metabolism, studies were undertaken to
determine whether the cell wall could be the site of action as has been proposed for muscle. …

Comparative biochemistry of hepatomas: IV. Isotope studies of glucose and fructose metabolism in liver tumors of different growth rates

MJ Sweeney, J Ashmore, HP Morris, G Weber - Cancer Research, 1963 - AACR
The metabolic fate of labeled fructose and glucose was compared in normal liver and in
hepatomas of different growth rates. For certain biochemical parameters a rough correlation with …

[HTML][HTML] B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors

…, M Yoshihara, M Beniazza, J Ashmore… - Nature …, 2023 - nature.com
Induced pluripotent stem cell (iPSC) reprogramming is inefficient and understanding the
molecular mechanisms underlying this inefficiency holds the key to successfully control cellular …

Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo

L Tosti, J Ashmore, BSN Tan, B Carbone… - Genome …, 2018 - genome.cshlp.org
The identification of transcription factor (TF) binding sites in the genome is critical to
understanding gene regulatory networks (GRNs). While ChIP-seq is commonly used to identify TF …

[PDF][PDF] Constitutively active SMAD2/3 are broad-scope potentiators of transcription-factor-mediated cellular reprogramming

T Ruetz, U Pfisterer, B Di Stefano, J Ashmore… - Cell Stem Cell, 2017 - cell.com
Reprogramming of cellular identity using exogenous expression of transcription factors (TFs)
is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative …