Triclosan (2,4,4′-trichloro-2′-hydroxy-diphenyl ether) is an antibacterial compound that has
been used in consumer products for about 40 years. The tolerability and safety of triclosan …

Paracelsus, Philippus Theophrastus Aureolus Bombastus von Hohenheim, the “father of
chemistry and the reformer of materia medica,” the “Luther of Medicine,” the “godfather of …

Studies were conducted to assess the safety of N-α-lauroyl-l-arginine ethyl ester monohydrochloride,
(LAE), a novel food preservative, or Mirenat-N (a 25% solution of LAE in propylene …

Ethical considerations are central to the design and conduct of all aspects of clinical research,
and for the participant, these considerations begin at recruitment. Ethics are paramount to …

… F/2b rats were continued through the same procedure as with F/lb generation through
production and weaning of F/3a and F/3b litters. Indices calculated for each generation mating …

This study evaluated the subchronic toxicity of selected halomethanes which are drinking
water contaminants. The compounds studied were trichloromethane, bromodichloromethane, …

A recent study in rats investigated the retail sweetener product, Granulated SPLENDA ® No
Calorie Sweetener (Splenda) (Abou-Donia et al., 2008. Splenda alters gut microflora and …

Ethyl acrylate or methyl methacrylate have been added to the drinking water of rats in
concentrations of 0, 6–7, 60–70, and 2000 ppm for a period of two years. On the basis of fluid and …

With the approval for use in foods in Japan and the United States, the use of diacylglycerol (DAG)
oil in fat-based products may become extensive due to equivalent physicochemical …

Oral LD50 values were 132 mg/kg for male rats, 126 mg/kg for female rats, 71 mg/kg for male
rabbits, and approximately 250 mg/kg for dogs. The percutaneous LD50 for male rabbits …