The distribution of bound propranolol between the different human serum proteins

…, R ZINI, P D'ATHIS, JP TILLEMENT, JR BOISSIER - Molecular …, 1980 - ASPET
Propranolol binding to the main, isolated, serum proteins was measured by equilibrium dialysis
and compared to its overall binding in serum measured by the same method. The results …

Rotational behaviour after unilateral intranigral injection of muscimol in rats.

…, C Dumont, JR Boissier - European journal of …, 1977 - psycnet.apa.org
Muscimol alone was injected into the substantia nigra of 44 male Sprague-Dawley rats in
doses ranging from 2 ng to 2 μg. Following the injection, Ss showed a contralateral (C) circling …

Biochemical assessment of the central 5-HT agonist activity of RU 24969 (a piperidinyl indole)

C Euvrard, JR Boissier - European Journal of Pharmacology, 1980 - Elsevier
The most potent compound of a series of piperidinyl indole derivatives which decrease 5-hydroxyindole
acetic acid (5-HIAA) levels in rat brain-stem was chosen for further study on the …

Antidopaminergic effect of estrogens at the striatal level.

C Euvrard, C Oberlander, JR Boissier - Journal of Pharmacology and …, 1980 - ASPET
The present study investigates the possibility that a potent synthetic estrogen (moxestrol)
possesses an antidopaminergic effect at the striatal level. Moxestrol and other estrogens, but …

Benzamides and classical neuroleptics: comparison of their actions using 6 apomorphine-induced effects

AJ Puech, P Simon, JR Boissier - European Journal of Pharmacology, 1978 - Elsevier
The effects of 6 benzamides and 8 classical neuroleptics were studied on 6 different
apomorphine-induced effects. These drugs did not antagonize all the effects in the same way. The …

Circling behaviour induced by dopamine releasers and/or uptake inhibitors during degeneration of the nigrostriatal pathway

…, C Euvrard, C Dumont, JR Boissier - European Journal of …, 1979 - Elsevier
A number of compounds which induced ipsilateral circling behaviour in rats with chronic
unilateral 6-hydroxy-dopamine (6-OHDA) destruction of the nigrostriatal dopamine (DA0 …

Studies on dl-4-(2-hydroxy-3-isopropylaminopropoxy)-indole (LB 46), a new potent beta adrenergic blocking drug

JF GIUDICELLI, H SCHMITT, JR BOISSIER - Journal of Pharmacology and …, 1969 - ASPET
The beta adrenergic blocking effects, the antiarrhythmic properties and the local anesthetic
activity of LB 46 have been investigated. In chloralose-anesthetized dogs, LB 46 was 10-to 40…

Antagonism by sulpiride of three apomorphine-induced effects in rodents

AJ Puech, P Simon, JR Boissier - European Journal of Pharmacology, 1976 - Elsevier
Three effects of apomorphine (hypothermia and climbing behavior in mice, stereotyped
behavior in rats) were studied. Sulpiride antagonized the two effects in mice but stereotyped …

Studies on the nature of the bronchial ß-adrenoreceptors

JR Boissier, C Advenier, JF Giudicelli, P Viars - European Journal of …, 1971 - Elsevier
The nature of brochial beta-receptors has been investigated in anaesthetized dogs by means
of a comparative study of practolol- and propranolol-isoprenaline antagonisms on airway …

Synthesis and central dopaminergic activities of (.+-.)-hexahydro-4H-indolo [3, 4-gh][1, 4] benzoxazine derivatives [(.+-.)-9-oxaergolines]

…, C Euvrard, C Dumont, JR Boissier… - Journal of Medicinal …, 1983 - ACS Publications
4, 5, 5a, 6, 6a, 7, 9, 10a-octahydro-4-(phenylmethyl)-7H-indolo [3, 4-gh][l, 4] benzoxazin-8-one
(8b) with LiAlH4. After debenzylation of the resulting amine 9a, the indoline ring of [5aRS-(…