The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical …
…, A Newman-Tancredi, V Pasteau, JM Rivet… - … of Pharmacology and …, 2003 - ASPET
Agomelatine (S20098) displayed pK i values of 6.4 and 6.2 at native (porcine) and cloned,
human (h)5-hydroxytryptamine (5-HT) 2C receptors, respectively. It also interacted with h5-HT …
human (h)5-hydroxytryptamine (5-HT) 2C receptors, respectively. It also interacted with h5-HT …
Serotonin2C receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and …
A Gobert, JM Rivet, F Lejeune, A Newman‐Tancredi… - Synapse, 2000 - Wiley Online Library
The present study evaluated, via a combined electrophysiological and dialysis approach, the
potential influence of serotonin (5‐HT) 2C as compared to 5‐HT 2A and 5‐HT 2B receptors …
potential influence of serotonin (5‐HT) 2C as compared to 5‐HT 2A and 5‐HT 2B receptors …
Agonist and antagonist actions of yohimbine as compared to fluparoxan at α2‐adrenergic receptors (AR) s, serotonin (5‐HT) 1A, 5‐HT1B, 5‐HT1D and dopamine D2 …
…, JP Nicolas, F Cogé, JP Galizzi, JA Boutin, JM Rivet… - Synapse, 2000 - Wiley Online Library
Herein, we evaluate the interaction of the α 2 ‐AR antagonist, yohimbine, as compared to
fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of …
fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of …
Glial D-Serine Gates NMDA Receptors at Excitatory Synapses in Prefrontal Cortex
…, FR Turpin, S Sacchi, J Dulong, T Shi, JM Rivet… - Cerebral …, 2012 - academic.oup.com
N-methyl-D-aspartate receptors (NMDARs) subserve numerous neurophysiological and
neuropathological processes in the cerebral cortex. Their activation requires the binding of …
neuropathological processes in the cerebral cortex. Their activation requires the binding of …
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of …
A Gobert, JM Rivet, V Audinot, A Newman-Tancredi… - Neuroscience, 1998 - Elsevier
In the present study, a novel and exceptionally sensitive method of high-performance liquid
chromatography coupled to coulometric detection, together with concentric dialysis probes, …
chromatography coupled to coulometric detection, together with concentric dialysis probes, …
Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of α2‐adrenergic and serotonin2C …
MJ Millan, A Gobert, JM Rivet… - European Journal of …, 2000 - Wiley Online Library
Mirtazapine displayed marked affinity for cloned, human α 2A ‐adrenergic (AR) receptors at
which it blocked noradrenaline (NA)‐induced stimulation of guanosine‐5′‐O‐(3‐[ 35 S]thio)…
which it blocked noradrenaline (NA)‐induced stimulation of guanosine‐5′‐O‐(3‐[ 35 S]thio)…
5‐HT6 receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia
…, A Dekeyne, M Séveno, JM Rivet… - EMBO Molecular …, 2012 - embopress.org
Cognitive deficits in schizophrenia severely compromise quality of life and are poorly
controlled by current antipsychotics. While 5‐HT 6 receptor blockade holds special promise, …
controlled by current antipsychotics. While 5‐HT 6 receptor blockade holds special promise, …
S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with …
…, F Lejeune, A Newman-Tancredi, JM Rivet… - … of Pharmacology and …, 2001 - ASPET
S33005 displayed marked affinity for native, rat, and cloned human serotonin (5-HT) transporters
(SERT) and less pronounced affinity for norepinephrine (NE) transporters (NET), while …
(SERT) and less pronounced affinity for norepinephrine (NE) transporters (NET), while …
S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models
…, T Sharp, A Daszuta, A Soumier, M Papp, JM Rivet… - …, 2008 - Springer
Rationale Serotonin (5-HT) 2C receptors are implicated in the control of mood, and their
blockade is of potential interest for the management of anxiodepressive states. Objectives …
blockade is of potential interest for the management of anxiodepressive states. Objectives …
Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA)
B Di Cara, R Maggio, G Aloisi, JM Rivet… - Journal of …, 2011 - Soc Neuroscience
“Ecstasy” [3,4-methylenedioxymetamphetamine (MDMA)] is of considerable interest in light
of its prosocial properties and risks associated with widespread recreational use. Recently, it …
of its prosocial properties and risks associated with widespread recreational use. Recently, it …