Although hormone and drug receptors have been studied by pharmacolo gists and
physiologists through most of this century, only within the past decade have the properties and …

There has been a rapid accumulation of new experimental data relating to the pharmacology
of! X2-adrenoceptors, including the identification of multiple receptor subtypes and new …

The unique properties of agonist binding to the frog erythrocyte beta-adrenergic receptor
include the existence of two affinity forms of the receptor. The proportion and relative affinity of …

Urotensin-II (U-II) is a vasoactive ‘somatostatin-like’ cyclic peptide which was originally
isolated from fish spinal cords 1 , 2 , and which has recently been cloned from man 3 . Here we …

… In the present review, Jeffrey Stadel, Shelagh Wilson and Derk Bergsma outline the rationale
and describe strategies for converting one large class of novel genes, orphan G protein-…

Chemokines play an important role in the regulation of endothelial cell (EC) function,
including proliferation, migration and differentiation during angiogenesis, and re-endothelialization …

… ) and subsequent analysis byNaDodSO4/polyacrylamide gel electrophoresis demonstratesan
altered mobility of receptor peptides from desensitized cells compared to controls [Stadel, J…

Despite the availability of efficient transcription and translation signals, some heterologous
gene products are not adequately expressed when introduced into prokaryotes and …

Scg1, the product of the Saccharomyces cerevisiae SCG1 (also called GPA1) gene, is
homologous to the a subunits of G proteins involved in signal transduction in mammalian cells. …

A human liver cDNA library was screened using a rat type 1 angiotensin II receptor cDNA
coding sequence as a probe. cDNA clones were isolated which encoded a protein of 359 …