The degradation of tritiated and unlabelled neurotensin (NT) following close intra-arterial
infusion of the peptides in ileal segments of anaesthetized dogs was examined. 2. Intact NT …

This study examined the role of nitric oxide (NO) in tonic inhibition of motor activity in isolated,
perfused canine ileal segments. Brief addition of N omega-nitro-L-arginine methyl ester (L-…

Perfusion with ([N-Me-Phe3,D-Pro4]morphiceptin (PL017)), [D-Pen2,5]enkephalin (DPDPE)
and MEt5 and Leu5 enkephalin induced circular muscle contractions and decreased …

A method was developed to study simultaneously 1) release of ACh from nerve varicosities
and terminals in and 2) motility of the myenteric plexus-free circular muscle of the canine …

The role of porcine galanin, infused arterially into isolated perfused canine ileal segments,
in modulating the tonically elevated neural release of vasoactive intestinal polypeptide and …

The presence of a cholinergic innervation of arterioles within the gut wall is suggested by
pharmacological studies of nerve mediated vasodilatation, but attempts to identify nerve cells …

Glucagon-like peptide-1 (GLP-1) modulates glucose levels following a meal, including by
inhibition of gastric emptying and intestinal transport. Intra-arterial injection of GLP-1 into the …

This study defined the cholecystokinin(CCK)/gastrin receptor subtypes at which CCK
octapeptide(CCK) and gastnn 17 (G17) act on motor functions of the intact canine gastrointestinal …

Peptide YY (PYY) and neuropeptide Y (NPY), infused into the quiescent isolated perfused
canine ileum, dose-dependently increased phasic activity of the circular muscle and …

Perfusion of ileal segments with tetrodotoxin; opioids, Met-enkephalin and dynorphin; and α
2 adrenoceptor agonist, BHT920, increased motility concomitant with the decreased VIP …