Cholecystokinin coexists with dopamine in mesolimbic neurons in mammalian brain. When
injected directly into the nucleus accumbens, cholecystokinin (CCK) potentiated dopamine (…

Pharmacological studies on the behavioral functions of sulfated cholecystokinin (CCK) in the
gut and in the brain require potent, specific antagonists to CCK. Compounds identffied as …

Bilateral microinjection of oxytocin (OXY) into the ventral tegmental area (VTA) of rat brain
produced a significant increase in grooming behaviors at doses from 100 pg to 400 ng. Sites …

High amplitude spiking representative of seizures, accompanied by an unusual motor
behavior pattern of rearing and forelimbic clonus resembling “boxing,” was elicited by …

Intracerebral microinjection of the cholinergic agonist, carbachol, into the medial prefrontal
cortex of the rat, induced a profound behavioral syndrome consisting of repetitive, …

The morphological and biochemical consequences of transplanting affected bone marrow
from donor BALB/c mice with a lysosomal storage disorder (BALB/c LSD) into normal recipient …

Feeding induced by 2-deoxyglucose was compared with feeding induced by food deprivation
in terms of antagonism by anorectic drugs and of anatomical site of action. Glucoprivic …

The distribution of low-affinity sodium-sensitive binding sites of [ 3 H]mazindol were studied
in rat hypothalamic nuclei. Using microdissection methods, it was demonstrated that the …

A cholinergic projection from the dorsolateral tegmentum to the medial anterior cortex has
previously been shown to contain substance P and corticotropin releasing factor. Behavioral …

The discovery of neuropeptides in mammalian brain was followed by the iconoclastic revelation
that peptides coexist in the same neuron with classical neurotransmitters(Hökfelt et al., …