Co-evolution of tumor cells and their microenvironment

K Polyak, I Haviv, IG Campbell - Trends in genetics, 2009 - cell.com
Increasing evidence indicates that tumor–stromal cell interactions have a crucial role in tumor
initiation and progression. These interactions modify cellular compartments, leading to the …

Sleep EEG changes during adolescence: an index of a fundamental brain reorganization

I Feinberg, IG Campbell - Brain and cognition, 2010 - Elsevier
Delta (1–4Hz) EEG power in non-rapid eye movement (NREM) sleep declines massively
during adolescence. This observation stimulated the hypothesis that during adolescence the …

EEG recording and analysis for sleep research

IG Campbell - Current protocols in neuroscience, 2009 - Wiley Online Library
The electroencephalogram (EEG) is the most common tool used in sleep research. This unit
describes the methods for recording and analyzing the EEG. Detailed protocols describe …

Mutation of the PIK3CA Gene in Ovarian and Breast Cancer

IG Campbell, SE Russell, DYH Choong… - Cancer research, 2004 - AACR
… Philp AJ, Campbell IG, Leet C, et al The phosphatidylinositol 3′-kinase p85alpha gene is
… Jiang X, Morland SJ, Hitchcock A, Thomas E, Campbell IG Allelotyping of endometriosis with …

The phosphatidylinositol 3′-kinase p85α gene is an oncogene in human ovarian and colon tumors

AJ Philp, IG Campbell, C Leet, E Vincan, SP Rockman… - Cancer research, 2001 - AACR
Phosphatidylinositol 3′-kinases (PI3ks) are a family of lipid kinases that play a crucial role
in a wide range of important cellular processes associated with malignant behavior including …

Folate-binding protein is a marker for ovarian cancer

IG Campbell, TA Jones, WD Foulkes, J Trowsdale - Cancer research, 1991 - AACR
We describe the isolation of a complementary DNA (cDNA) sequence encoding the ovarian
cancer-associated antigen recognized by monoclonal antibody MOv18 and its identification …

Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors

…, G Chenevix-Trench, EJ Thomas, IG Campbell - Cancer research, 1998 - AACR
… and Campbell. IG Allelotyping of endometriosis with adjacent ovarian carcinoma reveals …
IG Microsatcllite analysis of endometriosis reveals loss of hcterozygosity at candidate ovarian …

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

…, ER Thompson, SR Lakhani, AC Vargas, IG Campbell… - Rna, 2011 - rnajournal.cshlp.org
Long noncoding RNAs (lncRNAs) are increasingly recognized to play major regulatory roles
in development and disease. To identify novel regulators in breast biology, we identified …

CONTRA: copy number analysis for targeted resequencing

…, RW Tothill, SK Halgamuge, IG Campbell… - …, 2012 - academic.oup.com
Motivation: In light of the increasing adoption of targeted resequencing (TR) as a cost-effective
strategy to identify disease-causing variants, a robust method for copy number variation (…

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

…, KL Gorringe, K Polyak, I Haviv, IG Campbell - Nature …, 2008 - nature.com
There is increasing evidence showing that the stromal cells surrounding cancer epithelial
cells, rather than being passive bystanders, might have a role in modifying tumor outgrowth. …