User profiles for Ho Thanh Tu

Thanh Tu Ho

Cornell University
Verified email at cornell.edu
Cited by 106

Trapoxin A analogue as a selective nanomolar inhibitor of HDAC11

TT Ho, C Peng, E Seto, H Lin - ACS Chemical Biology, 2023 - ACS Publications
Histone deacetylases (HDACs) are enzymes that regulate many important biological
pathways. There is a need for the development of isoform-selective HDAC inhibitors for further …

Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating …

…, P Mondal, N Sang, G Liu, X Lu, TT Ho… - Journal of Medicinal …, 2023 - ACS Publications
Recent studies have shown that the epigenetic protein histone deacetylase 11 (HDAC11) is
highly expressed in the brain and critically modulates neuroimmune functions, making it a …

Garcinol is an HDAC11 inhibitor

SI Son, D Su, TT Ho, H Lin - ACS chemical biology, 2020 - ACS Publications
Garcinol is a natural product from the Garcinia Indica fruit and is well-known as an antioxidant,
anti-inflammatory, and anticancer agent. However, the understanding of its mechanism of …

Slow-, tight-binding inhibition of CYP17A1 by abiraterone redefines its kinetic selectivity and dosing regimen

EJY Cheong, PC Nair, RWY Neo, HT Tu, F Lin… - … of Pharmacology and …, 2020 - ASPET
Substantial evidence underscores the clinical efficacy of inhibiting CYP17A1-mediated
androgen biosynthesis by abiraterone for treatment of prostate oncology. Previous structural …

Adaptation to flood risks in Ho Chi Minh City, Vietnam

T Thanh Tu, V Nitivattananon - International Journal of Climate …, 2011 - emerald.com
Purpose – This paper aims to present part of the research results in developing an
adaptation process to cope with flood risk in coastal cities under the impact of climate change …

Abstract 2395 HDAC11's de-fatty acylation of SF3B2 could provide new understanding of RNA splicing regulation and Liver Cancer progression

J Clements, C Peng, TT Ho, H Lin, E Seto - Journal of Biological Chemistry, 2024 - ASBMB
Liver cancer is the world's leading cause of cancer deaths and lacks effective tumor intrinsic
treatment avenues. In liver cancer patients, histone deacetylase 11 (HDAC11) is prognostic …

Study on the current status of exposure to pathogenic microorganisms and consumers' interest in milk tea

T Tran, NT Nguyen, TNT Thanh, HCT Tran… - Journal of Food …, 2023 - Wiley Online Library
The assurance of food safety is paramount, especially concerning ready‐to‐drink products
like milk tea. This research sought to gauge the safety perceptions of both student and office …

[HTML][HTML] A spherical fuzzy analytic hierarchy process (SF-AHP) and combined compromise solution (CoCoSo) algorithm in distribution center location selection: A case …

PT Kieu, VT Nguyen, VT Nguyen, TP Ho - Axioms, 2021 - mdpi.com
Logistics is an important service sector, contributing to improving the competitiveness of the
economy. Therefore, along with increasing the application of technology and effective …

Nonlinear PID control to improve the control performance of 2 axes pneumatic artificial muscle manipulator using neural network

TUDC Thanh, KK Ahn - Mechatronics, 2006 - Elsevier
The application of a robot to rehabilitation has become a matter of great concern because of
the requirement of functional recovery therapy of arm or limb. A novel pneumatic artificial …

Green synthesized nano-silver/cellulose aerogel as a robust active and recyclable catalyst towards nitrophenol hydrogenation

TGT Ho, DPT Truong, HB Nguyen, BL Do… - Chemical Engineering …, 2023 - Elsevier
Water contamination by hazardous aromatic nitro compounds is a serious problem, and
reduction in p-nitrophenol (PNP) by combining a catalyst and a reductant has been a topic of …