ISFM consensus guidelines on the diagnosis and management of feline chronic kidney disease

…, C Langston, HP Lefebvre… - Journal of feline …, 2016 - journals.sagepub.com
Practical relevance: Chronic kidney disease (CKD) is one of the most commonly diagnosed
diseases in older cats. In most cats, CKD is also a progressive disease and can be …

Plasma pharmacokinetics of alfaxalone in dogs after an intravenous bolus of Alfaxan-CD RTU

…, T Whittem, MG Ranasinghe, Q Li, HP Lefebvre - Veterinary anaesthesia …, 2006 - Elsevier
Objective To determine the pharmacokinetic parameters of alfaxalone in dogs after the
intravenous (IV) administration of clinical and supra-clinical doses of a 2-hydroxypropyl-beta-…

Spontaneous feline hypertension: clinical and echocardiographic abnormalities, and survival rate

V Chetboul, HP Lefebvre, C Pinhas… - Journal of Veterinary …, 2003 - Wiley Online Library
Systemic hypertension was diagnosed in 58 of 188 untreated cats referred for evaluation of
suspected hypertension‐associated ocular, neurologic, cardiorespiratory, and urinary …

Plasma exogenous creatinine clearance test in dogs: comparison with other methods and proposed limited sampling strategy

ADJ Watson, HP Lefebvre, D Concordet… - Journal of Veterinary …, 2002 - Wiley Online Library
Plasma clearance of creatinine was evaluated for assessment of glomerular nitration rate (GFR)
in dogs. In 6 healthy dogs (Experiment 1), we determined 24‐hour urine clearance of …

Feline CKD: Pathophysiology and risk factors—what do we know?

BS Reynolds, HP Lefebvre - Journal of feline medicine and …, 2013 - journals.sagepub.com
Practical relevance: Chronic kidney disease (CKD) is one of the most frequently encountered
disorders in cats, having increased in prevalence in recent decades. Although the …

Use of quantitative two-dimensional color tissue Doppler imaging for assessment of left ventricular radial and longitudinal myocardial velocities in dogs

…, AP Nicolle, JL Pouchelon, HP Lefebvre - American Journal of …, 2005 - Am Vet Med Assoc
Objective —To determine left ventricular free wall (LVFW) radial and longitudinal myocardial
contraction velocities in healthy dogs via quantitative 2-dimensional color tissue Doppler …

Comparative adverse cardiac effects of pimobendan and benazepril monotherapy in dogs with mild degenerative mitral valve disease: a prospective, controlled …

V Chetboul, HP Lefebvre… - Journal of veterinary …, 2007 - Wiley Online Library
Background: Pimobendan (PIMO) is an inodilator that may have some beneficial effects in
canine degenerative mitral valve disease (MVD). However, little information is available about …

Azotemia and glomerular filtration rate in dogs with chronic valvular disease

…, CC Sampedrano, HP Lefebvre - Journal of veterinary …, 2007 - Wiley Online Library
Background: Little information is available about the prevalence of renal dysfunction in dogs
with chronic valvular heart disease (CVD). Hypothesis: Azotemia and a decrease in …

Fractional excretion tests: a critical review of methods and applications in domestic animals

HP Lefebvre, O Dossin, C Trumel… - Veterinary Clinical …, 2008 - Wiley Online Library
The fractional excretion (FE) of a constituent by the kidney is the fraction of the amount filtered
by the glomerulus, which is excreted into urine. It is mostly determined for electrolytes, and …

Plasma N-terminal pro-B-type natriuretic peptide concentration helps to predict survival in dogs with symptomatic degenerative mitral valve disease regardless of and …

F Serres, JL Pouchelon, L Poujol, HP Lefebvre… - Journal of veterinary …, 2009 - Elsevier
OBJECTIVES: Although mitral valve disease (MVD) is the most common canine heart disease,
readily available prognostic markers of the disease are still lacking. The aim of this study …