User profiles for Harissios Vliagoftis

Harissios Vliagoftis

Verified email at ualberta.ca
Cited by 4762

Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials

H Vliagoftis, VD Kouranos, GI Betsi… - Annals of Allergy, Asthma & …, 2008 - Elsevier
OBJECTIVE: To evaluate the clinical evidence for the use of probiotics as a therapeutic
modality for allergic rhinitis (AR) and asthma. DATA SOURCES: PubMed was searched to …

[HTML][HTML] Airway epithelium interactions with aeroallergens: role of secreted cytokines and chemokines in innate immunity

VD Gandhi, H Vliagoftis - Frontiers in immunology, 2015 - frontiersin.org
Airway epithelial cells are the first line of defense against the constituents of the inhaled air,
which include allergens, pathogens, pollutants, and toxic compounds. The epithelium not …

The protooncogene c-kit and c-kit ligand in human disease

H Vliagoftis, AS Worobec, DD Metcalfe - Journal of Allergy and Clinical …, 1997 - Elsevier
… Author links open overlay panel Harissios Vliagoftis MD , Alexandra S. Worobec MD ,
Dean D. Metcalfe MD … Reprint requests: Harissios Vliagoftis, MD, Laboratory of Allergic …

Proteinase-activated receptor-2–mediated matrix metalloproteinase-9 release from airway epithelial cells

H Vliagoftis, A Schwingshackl, CD Milne… - Journal of allergy and …, 2000 - Elsevier
Background: Matrix metalloproteinases (MMPs) digest extracellular matrix components and
might be important mediators of tissue remodeling. Proteinase activated receptor-2 (PAR-2) …

Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c‐kit proto‐oncogene

M Sundström, H Vliagoftis, P Karlberg… - …, 2003 - Wiley Online Library
The human mast cell line (HMC)‐1 cell line is growth‐factor independent because of a
constitutive activity of the receptor tyrosine kinase Kit. Such deregulated Kit activity has also been …

AAAAI Mast Cell Disorders Committee Work Group Report: mast cell activation syndrome (MCAS) diagnosis and management

…, SS Mustafa, A Ravi, MC Tobin, H Vliagoftis… - Journal of Allergy and …, 2019 - Elsevier
Our current recommendations for diagnosing and treating primary mast cell (MC) activation
syndrome make use of the latest studies and consensus guidelines for clinically recognizing …

Protease allergens as initiators–regulators of allergic inflammation

WT Soh, J Zhang, MD Hollenberg, H Vliagoftis… - Allergy, 2023 - Wiley Online Library
Tremendous progress in the last few years has been made to explain how seemingly harmless
environmental proteins from different origins can induce potent Th2‐biased inflammatory …

[HTML][HTML] The Allergic Rhinitis–Clinical Investigator Collaborative (AR-CIC): nasal allergen challenge protocol optimization for studying AR pathophysiology and …

…, MÈ Boulay, LP Boulet, PK Keith, H Vliagoftis… - Allergy, Asthma & …, 2015 - Springer
Background The Nasal Allergen Challenge (NAC) model allows the study of Allergic Rhinitis
(AR) pathophysiology and the proof of concept of novel therapies. The Allergic Rhinitis – …

Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation

…, JR Gordon, MD Hollenberg, H Vliagoftis - The Journal of …, 2011 - journals.aai.org
We have shown that proteinase-activated receptor-2 (PAR 2) activation in the airways leads
to allergic sensitization to concomitantly inhaled Ags, thus implicating PAR 2 in the …

House dust mite interactions with airway epithelium: role in allergic airway inflammation

…, M Asaduzzaman, D Nahirney, H Vliagoftis - Current allergy and …, 2013 - Springer
House dust mite (HDM) allergens are the most prevalent allergens associated with asthma
and rhinitis around the world. The mechanisms of allergic sensitization and allergic airway …