Effect of fracture properties and surface morphology on wear of DLC coatings at severe contact condition

…, N Umehara, T Tokoroyama, WY Lee, H Takamatsu… - Tribology …, 2022 - Elsevier
The present study shows how the fracture properties and surface morphology of diamond-like
carbon (DLC) coatings affect their wear properties. Nine types of DLC coatings with …

Pharmacological properties of YM-254890, a specific Gαq/11 inhibitor, on thrombosis and neointima formation in mice

…, T Uemura, T Shigenaga, H Takamatsu… - Thrombosis and …, 2005 - thieme-connect.com
The pharmacological properties of YM-254890,a specific Gα q/11 inhibitor, on acute thrombosis
and chronic neointima formation after vascular injury have been investigated. FeCl 3 …

Effect of YM-254890, a specific Gαq/11 inhibitor, on experimental peripheral arterial disease in rats

T Uemura, H Takamatsu, T Kawasaki… - European journal of …, 2006 - Elsevier
The protective effect of YM-254890, a specific Gα q/11 inhibitor, on laurate-induced peripheral
arterial disease in rats was compared with those of prostaglandin E 1 (PGE 1 ), beraprost, …

Effects of neurokinin 3 receptor antagonist fezolinetant on hot flash-like symptoms in ovariectomized rats

A Tahara, H Takamatsu, A Ohtake… - European Journal of …, 2021 - Elsevier
The majority of women experience vasomotor symptoms (VMS), such as hot flashes and
night sweats, during the menopausal transition. Recent evidence strongly suggests a …

L‐type Ca2+ channels serve as a sensor of the SR Ca2+ for tuning the efficacy of Ca2+‐induced Ca2+ release in rat ventricular myocytes

H Takamatsu, T Nagao, H Ichijo… - The Journal of …, 2003 - Wiley Online Library
L‐type Ca2+ channels serve as a sensor of the SR Ca2+ for tuning the efficacy of Ca2+‐induced
Ca2+ release in rat ventricular myocytes - Takamatsu - 2003 - The Journal of …

Effect of inhibition of Na+ K+ ATpase on the prostacyclin generation of cultured human vascular endothelial cells

M Nakagawa, H Takamatsu, T Toyoda, S Sawada… - Life sciences, 1987 - Elsevier
Prostacyclin (PGI 2 ) generation of cultured human vascular endothelial cells (VEC) was
observed coincidentally with the increase of 45 Ca net influx. Ca ionophore A23187 enhanced …

Study on Physiological Roles of Stimulation of Prostaglandin E2 Receptor Subtype EP2 in Urethral Function in Rats

R Kurihara, K Ishizu, H Takamatsu… - LUTS: Lower Urinary …, 2016 - Wiley Online Library
Objectives We investigated the relaxant effect of stimulation of prostaglandin E 2 ( PGE 2 )
receptor subtype EP2 as well as the involvement of a cyclic AMP ( cAMP )‐dependent …

Prostacyclin generation by cultured human vascular endothelial cells with reference to angiotensin I-converting enzyme

S SAWADA, T TOYODA, H TAKAMATSU… - Japanese circulation …, 1986 - jstage.jst.go.jp
ROSTACYCLIN (PGIz) generation has been known to be regulated by several endogenous
mediators and various agents. It is well known that captopril is an inhibitor of angiotensin I-…

Potentiation of muscarinic M3 receptor activation through a new allosteric site with a novel positive allosteric modulator ASP8302

R Okimoto, K Ino, K Ishizu, H Takamatsu… - … of Pharmacology and …, 2021 - ASPET
Muscarinic M 3 (M 3 ) receptors mediate a wide range of acetylcholine (ACh)-induced functions,
including visceral smooth-muscle contraction and glandular secretion. Positive allosteric …

Modulation of prostacyclin generation in cultured human vascular endothelial cells and the effects of human α-natriuretic polypeptide

M Nakagawa, H Takamatsu, T Toyoda… - … et Biophysica Acta (BBA …, 1986 - Elsevier
Vascular endothelial cells have been known to possess not only a barrier function but also
other biologically important functions maintaining vascular homeostasis. Among these, the …