[HTML][HTML] Potential therapeutic target for aging and age-related neurodegenerative diseases: the role of acid sphingomyelinase
MH Park, HK Jin, J Bae - Experimental & molecular medicine, 2020 - nature.com
Aging, which is associated with age-related changes in physiological processes, is the most
significant risk factor for the development and progression of neurodegenerative diseases, …
significant risk factor for the development and progression of neurodegenerative diseases, …
Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease …
JK Lee, HK Jin, S Endo, EH Schuchman, JE Carter… - Stem …, 2010 - academic.oup.com
Alzheimer's disease (AD) is characterized by the deposition of amyloid-β peptide (Aβ) and the
formation of neurofibrillary tangles. Transplantation of bone marrow-derived mesenchymal …
formation of neurofibrillary tangles. Transplantation of bone marrow-derived mesenchymal …
[HTML][HTML] Sphingolipids in neuroinflammation: A potential target for diagnosis and therapy
JY Lee, HK Jin, J Bae - BMB reports, 2020 - ncbi.nlm.nih.gov
Sphingolipids are ubiquitous building blocks of eukaryotic cell membranes that function as
signaling molecules for regulating a diverse range of cellular processes, including cell …
signaling molecules for regulating a diverse range of cellular processes, including cell …
Polymorphisms and the differential antiviral activity of the chicken Mx gene
JH Ko, HK Jin, A Asano, A Takada, A Ninomiya… - Genome …, 2002 - genome.cshlp.org
The nucleotide sequence of chicken Mx cDNA was reported earlier using the White Leghorn
breed in Germany, but it showed no enhanced resistance to viruses. In this study, the …
breed in Germany, but it showed no enhanced resistance to viruses. In this study, the …
Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through …
…, W Oh, YS Yang, JG Suh, BH Lee, HK Jin… - Neurobiology of …, 2012 - Elsevier
Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSC) have a potential
therapeutic role in the treatment of neurological disorders, but their current clinical usage …
therapeutic role in the treatment of neurological disorders, but their current clinical usage …
Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease …
The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) has
recently been explored in various pathological conditions of the central nervous system (CNS…
recently been explored in various pathological conditions of the central nervous system (CNS…
Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with …
…, JE Carter, M Modo, EH Schuchman, HK Jin - Stem …, 2007 - academic.oup.com
Recent studies have shown that bone marrow-derived MSCs (BM-MSCs) improve neurological
deficits when transplanted into animal models of neurological disorders. However, the …
deficits when transplanted into animal models of neurological disorders. However, the …
Stromal vascular fraction from adipose tissue forms profound vascular network through the dynamic reassembly of blood endothelial cells
Objective— Tremendous efforts have been made to establish effective therapeutic
neovascularization using adipose tissue-derived stromal vascular fraction (SVF), but the efficiency is …
neovascularization using adipose tissue-derived stromal vascular fraction (SVF), but the efficiency is …
The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease
…, H Lee, J Shin, JE Carter, T Sakamoto, HK Jin… - Neuroscience …, 2010 - Elsevier
The neuropathological hallmarks of Alzheimer's disease (AD) include the presence of
extracellular amyloid-β peptide (Aβ) in the form of amyloid plaques in the brain parenchyma and …
extracellular amyloid-β peptide (Aβ) in the form of amyloid plaques in the brain parenchyma and …
Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease
JK Lee, HK Jin, MH Park, B Kim, PH Lee… - Journal of Experimental …, 2014 - rupress.org
… JK Lee and HK Jin contributed equally to this paper. … He performed experiments and analyzed
data, JK Lee, HK Jin, and JS Bae designed the study and wrote the paper. EH Schuchman …
data, JK Lee, HK Jin, and JS Bae designed the study and wrote the paper. EH Schuchman …