In 1964, the psychoactive ingredient of Cannabis sativa, Δ 9 -tetrahydrocannabinol (THC),
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …

There is now a large body of data indicating that the cannabinoid receptor type 2 (CB2) is
linked to a variety of immune events. This functional relevance appears to be most salient in …

The genus Naegleria is comprised of a group of free-living ameboflagellates found in
diverse habitats worldwide. Over 30 species have been isolated from soil and water but only …

The effect of cannabinoids on the induction of cytokine mRNA by rat microglial cells was
examined. Exposure of neonatal rat cortical microglial cells to the exogenous cannabinoid δ 9 ‐…

The cannabinoid receptor family consists of two inhibitory G‐protein‐coupled receptors,
CB1 and CB2. CB1 is distributed primarily in neural tissue, whereas CB2 is distributed …

Activated glial cells have been implicated in the neuropathogenesis of many infectious and
inflammatory diseases of the brain. A number of inflammatory mediators have been …

Upon activation, brain microglial cells release proinflammatory mediators, such as nitric oxide
(NO), which may play an important role in the central nervous system antibacterial, antiviral…

Free‐living amebae belonging to the genus Acanthamoeba are the causative agents of
granulomatous amebic encephalitis, a chronic progressive disease of the central nervous system…

The study of marijuana cannabinoid biology has led to many important discoveries in
neuroscience and immunology. These studies have uncovered a new physiological system, the …

Illicit drugs such as amphetamines, cocaine, marijuana, and opiates alter immune function
and decrease host resistance to microbes in vitro and in experimental animal models. Effects …