Objective: Sympathetic nervous system activity in the myocardium is increased in patients
with heart failure. However, the in vivo mechanisms responsible for β-adrenoceptor-mediated …

Reactive oxygen species (ROS) participate in cardioprotection of ischemic reperfusion (I/R)
injury via preconditioning mechanisms. Mitochondrial ROS have been shown to play a key …

Reactive oxygen species (ROS) are key mediators in signal transduction of angiotensin II (Ang
II). However, roles of vascular mitochondria, a major intracellular ROS source, in …

It has recently been shown that glomerular mesangial injury is associated with increases in
renal cortical reactive oxygen species (ROS) levels in rats treated chronically with …

Peptide hormone Angiotensin II (Ang II) activates NAD(P)H oxidase, via AT1 receptors leading
to increased generation of reactive oxygen species (ROS), such as the superoxide anion (…

Advancing the clean transition of energy structure and reducing air pollution levels are
important actions for achieving sustainable urban development. In this study, we analyze the …

The glymphatic system contributes to the clearance of amyloid-β from the brain and is
disrupted in Alzheimer’s disease. However, whether the system is involved in the removal of α-…

Backgrounds Solid evidence has demonstrated that psychoemotional stress induced alteration
of hair cycle through neuropeptide substance P (SP) mediated immune response, the …

Treatment with cyclosporine A (CysA), a potent immunosuppressive agent, is associated
with systemic and renal vasoconstriction, leading to hypertension. The present study was …

Elevated activities of the sympathetic nerve and renin–angiotensin systems are common
features of heart failure. This study was designed to investigate the roles of the AT1 receptor in …