A rational nomenclature for naming peptide toxins from spiders and other venomous animals
Molecular toxinology research was initially driven by an interest in the small subset of animal
toxins that are lethal to humans. However, the realization that many venomous creatures …
toxins that are lethal to humans. However, the realization that many venomous creatures …
[HTML][HTML] Spider-venom peptides as bioinsecticides
Over 10,000 arthropod species are currently considered to be pest organisms. They are
estimated to contribute to the destruction of ~14% of the world’s annual crop production and …
estimated to contribute to the destruction of ~14% of the world’s annual crop production and …
Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads
…, DB Rupasinghe, SY Er, V Herzig, GM Nicholson… - Toxicon, 2012 - Elsevier
Voltage-gated sodium (Na V ) channels play a central role in the propagation of action potentials
in excitable cells in both humans and insects. Many venomous animals have therefore …
in excitable cells in both humans and insects. Many venomous animals have therefore …
[HTML][HTML] Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge
…, MEH Howden, GM Nicholson… - Nature structural …, 2000 - nature.com
We have isolated a family of insect-selective neurotoxins from the venom of the Australian
funnel-web spider that appear to be good candidates for biopesticide engineering. These …
funnel-web spider that appear to be good candidates for biopesticide engineering. These …
ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures
…, Q Kaas, GJ Binford, GM Nicholson… - Nucleic acids …, 2010 - academic.oup.com
ArachnoServer ( www.arachnoserver.org ) is a manually curated database providing information
on the sequence, structure and biological activity of protein toxins from spider venoms. …
on the sequence, structure and biological activity of protein toxins from spider venoms. …
Fighting the global pest problem: preface to the special Toxicon issue on insecticidal toxins and their potential for insect pest control
GM Nicholson - Toxicon, 2007 - Elsevier
Arthropod pests are responsible for major crop devastation and are vectors for the transmission
of new and re-emerging diseases in humans and livestock. Despite many years of …
of new and re-emerging diseases in humans and livestock. Despite many years of …
Venomics: unravelling the complexity of animal venoms with mass spectrometry
…, L Quinton, GM Nicholson - Journal of mass …, 2008 - Wiley Online Library
Animal venoms and toxins are now recognized as major sources of bioactive molecules that
may be tomorrow's new drug leads. Their complexity and their potential as drug sources …
may be tomorrow's new drug leads. Their complexity and their potential as drug sources …
[HTML][HTML] The biochemical toxin arsenal from ant venoms
Ants (Formicidae) represent a taxonomically diverse group of hymenopterans with over 13,000
extant species, the majority of which inject or spray secretions from a venom gland. The …
extant species, the majority of which inject or spray secretions from a venom gland. The …
[HTML][HTML] Ciguatoxins: Cyclic polyether modulators of voltage-gated Iion channel function
GM Nicholson, RJ Lewis - Marine Drugs, 2006 - mdpi.com
Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are
responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish …
responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish …
Diversity of peptide toxins from stinging ant venoms
Ants (Hymenoptera: Formicidae) represent a taxonomically diverse group of arthropods
comprising nearly 13,000 extant species. Sixteen ant subfamilies have individuals that possess …
comprising nearly 13,000 extant species. Sixteen ant subfamilies have individuals that possess …